Amanda Tarullo - US grants
Affiliations: | 2008-2011 | New York State Psychiatric Institute/Columbia University Medical Center, New York, NY, United States |
We are testing a new system for linking grants to scientists.
The funding information displayed below comes from the NIH Research Portfolio Online Reporting Tools and the NSF Award Database.The grant data on this page is limited to grants awarded in the United States and is thus partial. It can nonetheless be used to understand how funding patterns influence mentorship networks and vice-versa, which has deep implications on how research is done.
You can help! If you notice any innacuracies, please sign in and mark grants as correct or incorrect matches.
High-probability grants
According to our matching algorithm, Amanda Tarullo is the likely recipient of the following grants.| Years | Recipients | Code | Title / Keywords | Matching score |
|---|---|---|---|---|
| 2015 — 2016 | Tarullo, Amanda | R03Activity Code Description: To provide research support specifically limited in time and amount for studies in categorical program areas. Small grants provide flexibility for initiating studies which are generally for preliminary short-term projects and are non-renewable. |
Hair Cortisol as a Biomarker of Chronic Early Life Stress @ Boston University (Charles River Campus) ? DESCRIPTION: Children who experience chronic stress in early childhood are at risk for poor physical and mental health in adulthood. Early life stress shapes biological stress systems, with lifelong health consequences. Given the powerful long term implications of early life stress for public health, it is important to investigate how chronic early life stress exerts such far-reachin effects and which environmental stressors have the greatest impact on biological stress. Young children depend on sensitive caregivers to provide social buffering, protecting the developing brain from being exposed to too much of the stress hormone cortisol. However, poverty, household chaos, and parenting stress can disrupt this social buffering and may increase exposure to the stress hormone cortisol. To fully understand this process, a biological marker of chronic stress in infancy and early childhood is critically needed. Salivary cortisol, the most widely used marker of biological stress, measures acute rather than chronic stress, and salivary cortisol levels vary greatly from day to day. Cortisol is deposited in the hair shaft as it grows, o hair cortisol measures chronic stress over several months with a single sample. We and others have demonstrated the feasibility of measuring hair cortisol in young children. Yet much remains unknown about how this new method relates to established salivary cortisol methods. Salivary and hair measures may provide distinct information about the biological stress system, indexing daily regulation versus cumulative exposure. It is critical for researchers to make informed decisions about whether to use hair or salivary cortisol measures or both, as we work toward a comprehensive understanding of the processes through which early life stress influences biological stress systems. The current study will measure hair and salivary cortisol in 80 infants and 80 preschool children. Our first objective is to examine the extent to which hair cortisol and diurnal salivary cortisol measures are related in young children. Our second objective is to understand how established early life stressors relate to hair cortisol levels in young children. We will assess maternal sensitivity; maternal hair cortisol; maternal and paternal perceived stress; sleep; breastfeeding; childcare; fearfulness; household chaos; and socioeconomic status (SES) as predictors of this hair cortisol measure of chronic stress. This essential research will yield valuable data about how the innovative hair cortisol measure compares to ubiquitous salivary cortisol measures for two age cohorts, infancy and preschool, and how it relates to environmental stressors. Results will move the field forward in the quest to fully understand how early life stress shapes the development of biological stress systems. Ultimately, this knowledge will inform targeted prevention and intervention approaches to buffer young children from the biological consequences of early life stress, thus reducing long term public health burden. |
0.922 |
| 2020 — 2021 | Tarullo, Amanda | R01Activity Code Description: To support a discrete, specified, circumscribed project to be performed by the named investigator(s) in an area representing his or her specific interest and competencies. |
@ Boston University (Charles River Campus) PROJECT SUMMARY/ABSTRACT Socioeconomic health disparities in sleep and behavior problems are evident from early childhood. Young children in low-income families are at high risk of sleep and behavior problems, which often co-occur and predict long-term poor mental and physical health. These problems cause added strain in families that are already facing multiple poverty-related stressors, and family dysfunction in turn contributes to persistence and worsening of sleep and behavior problems. Engaging the family is essential to treating co-morbid sleep and behavior problems and preventing entrenched health disparities. Family interventions enhance child health outcomes; moreover, because child sleep, child behavior, and family functioning are intertwined, a successful intervention that addresses either sleep or behavior may lead to improvements both within and across domains. However, low-income families are often reluctant to seek or accept early intervention. Difficulty enrolling and retaining families undermines potential health benefits. Stigma associated with treating behavior problems also discourages families from accepting treatment. This project determines how best to overcome barriers to treatment in low-income families of children with co-morbid sleep and behavior problems. We compare how low-income families respond to two empirically-supported home visiting interventions, one treating sleep and the other treating behavior. Both are designed to address cultural, motivational, and logistical barriers to engagement. We also take the innovative approach of testing whether giving families a choice between a sleep or behavior intervention, so that the initial frame with which they enter the intervention relationship is one of self-determination, enhances family engagement and child outcomes. With a randomized, controlled trial design, we test effects of intervention (sleep vs. behavior), engagement, and family input (choice vs. assigned) on child symptoms and family functioning, and assess which intervention families most prefer, engage with, and value. We will enroll 500 low-income toddlers with co-morbid sleep and behavior problems, randomized to 4 home-visiting interventions: sleep, behavior, family choice (sleep or behavior), and an active control. At baseline and at 1, 5, and 9 months post- intervention, we will assess child sleep and behavior and family functioning. We will measure family preference, engagement, and perceived value of each intervention. Aim 1 is to examine effects of evidence- based sleep and behavior interventions in young low-income children with co-morbid sleep and behavior problems on child sleep and behavior and family functioning. Aim 2 is to determine whether parents prefer, engage with, and value a sleep or behavior intervention more. Aim 3 is to examine if giving families a choice of intervention results in higher engagement, higher perceived value and better family and child outcomes than assignment to intervention. By informing best practices for engaging low-income families to treat co-morbid sleep and behavior problems, results will be critical to reducing health disparities for children living in poverty. |
0.922 |