Jeff W. Barclay

Affiliations: 
University of Liverpool, Liverpool, England, United Kingdom 
Area:
Exocytosis, synaptic transmission, C. elegans
Website:
http://www.liv.ac.uk/physiology/root/department%20of%20physiology/research/barclay/index.htm
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"Jeff Barclay"
Mean distance: 16.39 (cluster 6)
 
SNBCP

Parents

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R Meldrum Robertson grad student 1996-2001 Queen's University, Canada
 (Environmentally -induced thermoprotection of insect motor control.)
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Publications

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Chen X, Barclay JW, Burgoyne RD, et al. (2015) Using C. elegans to discover therapeutic compounds for ageing-associated neurodegenerative diseases. Chemistry Central Journal. 9: 65
Chen X, McCueF HV, Wong SQ, et al. (2015) Ethosuximide ameliorates neurodegenerative disease phenotypes by modulating DAF-16/FOXO target gene expression. Molecular Neurodegeneration. 10: 51
McCue HV, Chen X, Barclay JW, et al. (2015) Expression profile of a Caenorhabditis elegans model of adult neuronal ceroid lipofuscinosis reveals down regulation of ubiquitin E3 ligase components. Scientific Reports. 5: 14392
Kashyap SS, Johnson JR, McCue HV, et al. (2014) Caenorhabditis elegans dnj-14, the orthologue of the DNAJC5 gene mutated in adult onset neuronal ceroid lipofuscinosis, provides a new platform for neuroprotective drug screening and identifies a SIR-2.1-independent action of resveratrol. Human Molecular Genetics. 23: 5916-27
Johnson JR, Kashyap S, Rankin K, et al. (2013) Rab-3 and unc-18 interactions in alcohol sensitivity are distinct from synaptic transmission. Plos One. 8: e81117
Martin VM, Johnson JR, Haynes LP, et al. (2013) Identification of key structural elements for neuronal calcium sensor-1 function in the regulation of the temperature-dependency of locomotion in C. elegans. Molecular Brain. 6: 39
Edwards MR, Johnson JR, Rankin K, et al. (2012) PKC-2 phosphorylation of UNC-18 Ser322 in AFD neurons regulates temperature dependency of locomotion. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 7042-51
Barclay JW, Morgan A, Burgoyne RD. (2012) Neurotransmitter release mechanisms studied in Caenorhabditis elegans. Cell Calcium. 52: 289-95
Jorgacevski J, Potokar M, Grilc S, et al. (2011) Munc18-1 tuning of vesicle merger and fusion pore properties. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 9055-66
Graham ME, Prescott GR, Johnson JR, et al. (2011) Structure-function study of mammalian Munc18-1 and C. elegans UNC-18 implicates domain 3b in the regulation of exocytosis. Plos One. 6: e17999
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