T. Jake Liang

Affiliations: 
2013- NIH (NIDDK) 
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"T. Liang"
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Children

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Adam Rolt grad student (Chemistry Tree)
Yaron Rotman post-doc

Collaborators

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Kevin G. Chen collaborator 2013- NIH (NIDDK)
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Publications

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Xia Y, Cheng X, Nilsson T, et al. (2023) Nucleolin binds to and regulates transcription of hepatitis B virus covalently closed circular DNA minichromosome. Proceedings of the National Academy of Sciences of the United States of America. 120: e2306390120
Liang TJ, Law JLM, Pietschmann T, et al. (2023) Challenge Inoculum for Hepatitis C Virus Controlled Human Infection Model. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 77: S257-S261
Rid A, Feld JJ, Liang TJ, et al. (2023) Ethics of Controlled Human Infection Studies With Hepatitis C Virus. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 77: S216-S223
Chida T, Ishida Y, Morioka S, et al. (2023) Persistent hepatic IFN system activation in HBV-HDV infection determines viral replication dynamics and therapeutic response. Jci Insight. 8
Park SB, Irvin P, Hu Z, et al. (2022) Targeting the Fusion Process of SARS-CoV-2 Infection by Small Molecule Inhibitors. Mbio. e0323821
Uchida T, Park SB, Inuzuka T, et al. (2021) Genetically edited hepatic cells expressing the NTCP-S267F variant are resistant to hepatitis B virus infection. Molecular Therapy. Methods & Clinical Development. 23: 597-605
Gara N, Tana MM, Kattapuram M, et al. (2021) Prospective Study of Withdrawal of Antiviral therapy in Patients with Chronic Hepatitis B after Prolonged Virological Response. Hepatology Communications
Liang TJ, Feld JJ, Cox AL, et al. (2021) Controlled Human Infection Model - Fast Track to HCV Vaccine? The New England Journal of Medicine. 385: 1235-1240
Zhang M, Zhang Z, Imamura M, et al. (2021) Infection courses, virological features and IFN-α responses of HBV genotypes in cell culture and animal models. Journal of Hepatology
Rolt A, Talley DC, Park SB, et al. (2021) Discovery and Optimization of a 4-Aminopiperidine Scaffold for Inhibition of Hepatitis C Virus Assembly. Journal of Medicinal Chemistry
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