Amy Tam, Ph.D.

Johns Hopkins University, Baltimore, MD 
s.cerevisiae, membrane biology, ABC transporters, protein degradation mechanisms
"Amy Tam"
Mean distance: 21373.2 (cluster 53)


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Susan Michaelis grad student 2000 Johns Hopkins
 (Role of Ste24p in CaaX processing and N-terminal proteolysis of yeast a-factor.)
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Fung E, Kang L, Sapashnik D, et al. (2021) Fc-GDF15 glyco-engineering and receptor binding affinity optimization for body weight regulation. Scientific Reports. 11: 8921
Tevelev B, Patel H, Shields K, et al. (2021) Genetic Rearrangement During Site Specific Integration Event Facilitates Cell Line Development of a Bispecific Molecule. Biotechnology Progress. e3158
Root AR, Guntas G, Katragadda M, et al. (2021) Discovery and optimization of a novel anti-GUCY2c x CD3 bispecific antibody for the treatment of solid tumors. Mabs. 13: 1850395
Apgar JR, Tam ASP, Sorm R, et al. (2020) Modeling and mitigation of high-concentration antibody viscosity through structure-based computer-aided protein design. Plos One. 15: e0232713
Ngo KA, Kishimoto K, Davis-Turak J, et al. (2020) Dissecting the Regulatory Strategies of NF-κB RelA Target Genes in the Inflammatory Response Reveals Differential Transactivation Logics. Cell Reports. 30: 2758-2775.e6
Zhong X, Ma W, Meade CL, et al. (2018) A Transient CHO Expression Platform for Robust Antibody Production and Its Enhanced N-Glycan Sialylation on Therapeutic Glycoproteins. Biotechnology Progress
Weng Y, Ishino T, Sievers A, et al. (2018) Glyco-engineered Long Acting FGF21 Variant with Optimal Pharmaceutical and Pharmacokinetic Properties to Enable Weekly to Twice Monthly Subcutaneous Dosing. Scientific Reports. 8: 4241
Avery LB, Wade J, Wang M, et al. (2017) Establishing in vitro in vivo correlations to screen monoclonal antibodies for physicochemical properties related to favorable human pharmacokinetics. Mabs. 0
de Costa A, Tam A. (2017) Liability for providing a prognosis in surgical practice. The Medico-Legal Journal. 85: 145-147
Tumey LN, Li F, Rago B, et al. (2017) Site Selection: a Case Study in the Identification of Optimal Cysteine Engineered Antibody Drug Conjugates. The Aaps Journal
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