Alan Finkelstein, Ph.D.

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Alan Finkelstein received his Ph.D. from The Rockefeller University and was subsequently invited to join the faculty of the Albert Einstein College of Medicine, where he has remained. He has a long-term interest in transport across membranes, and a more recent fascination with protein translocation. His research has included the permeability properties of planar lipid bilayer membranes, the fusion of lipid vesicles with these membranes, and the properties of channels reconstituted in them. These properties include: water, nonelectrolyte and ion flow through the channels, single-file transport, and voltage gating. In work on diphtheria and the channel-forming colicins, his laboratory has discovered and studied protein translocation associated with their voltage gating. Work on the anthrax toxin has been concerned with how the channel-forming component of the toxin acts to unfold its other protein components and serves as conduit for their translocation.

Cross-listing: Chemistry Tree