Rena C. Baek, Ph.D.

Affiliations: 
Boston College, Newton, MA, United States 
Area:
metabolic therapy
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"Rena Baek"
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Parents

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Thomas N. Seyfried grad student 2008 Boston College
 (Therapeutic strategies for the ganglioside storage diseases.)
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Publications

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Bradbury AM, Cochran JN, McCurdy VJ, et al. (2013) Therapeutic response in feline sandhoff disease despite immunity to intracranial gene therapy. Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 1306-15
Baek RC, Broekman ML, Leroy SG, et al. (2010) AAV-mediated gene delivery in adult GM1-gangliosidosis mice corrects lysosomal storage in CNS and improves survival. Plos One. 5: e13468
Denny CA, Heinecke KA, Kim YP, et al. (2010) Restricted ketogenic diet enhances the therapeutic action of N-butyldeoxynojirimycin towards brain GM2 accumulation in adult Sandhoff disease mice. Journal of Neurochemistry. 113: 1525-35
Baek RC, Martin DR, Cox NR, et al. (2009) Comparative analysis of brain lipids in mice, cats, and humans with Sandhoff disease. Lipids. 44: 197-205
Mukherjee P, Faber AC, Shelton LM, et al. (2008) Thematic review series: sphingolipids. Ganglioside GM3 suppresses the proangiogenic effects of vascular endothelial growth factor and ganglioside GD1a. Journal of Lipid Research. 49: 929-38
Baek RC, Kasperzyk JL, Platt FM, et al. (2008) N-butyldeoxygalactonojirimycin reduces brain ganglioside and GM2 content in neonatal Sandhoff disease mice. Neurochemistry International. 52: 1125-33
McNally MA, Baek RC, Avila RL, et al. (2007) Peripheral nervous system manifestations in a Sandhoff disease mouse model: nerve conduction, myelin structure, lipid analysis. Journal of Negative Results in Biomedicine. 6: 8
Lee JP, Jeyakumar M, Gonzalez R, et al. (2007) Stem cells act through multiple mechanisms to benefit mice with neurodegenerative metabolic disease. Nature Medicine. 13: 439-47
Broekman ML, Baek RC, Comer LA, et al. (2007) Complete correction of enzymatic deficiency and neurochemistry in the GM1-gangliosidosis mouse brain by neonatal adeno-associated virus-mediated gene delivery. Molecular Therapy : the Journal of the American Society of Gene Therapy. 15: 30-7
Yin X, Baek RC, Kirschner DA, et al. (2006) Evolution of a neuroprotective function of central nervous system myelin. The Journal of Cell Biology. 172: 469-78
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