John D. McCorvy, Ph.D.
Affiliations: | Medicinal Chemistry and Molecular Pharmacology | Purdue University, West Lafayette, IN, United States |
Area:
Dopamine and Serotonin AgonistsGoogle:
"John McCorvy"Mean distance: 18.16 (cluster 11)
Parents
Sign in to add mentorDavid E. Nichols | grad student | 2012 | Purdue | |
(Mapping the binding site of the 5-HT2A receptor using mutagenesis and ligand libraries: Insights into the molecular actions of psychedelics.) |
Children
Sign in to add traineeDaniel J. Sprague | post-doc | 2021- | Medical College of Wisconsin (Chemistry Tree) |
Tyler G Fenske | post-doc | 2022- | Medical College of Wisconsin (Chemistry Tree) |
BETA: Related publications
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Publications
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Wallach J, Cao AB, Calkins MM, et al. (2023) Identification of 5-HT receptor signaling pathways associated with psychedelic potential. Nature Communications. 14: 8221 |
Rodriguez P, Laskowski LJ, Pallais JP, et al. (2023) Functional profiling of the G protein-coupled receptor C3aR1 reveals ligand-mediated biased agonism. The Journal of Biological Chemistry. 105549 |
Cameron LP, Benetatos J, Lewis V, et al. (2023) Beyond the 5-HT Receptor: Classic and Nonclassic Targets in Psychedelic Drug Action. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 43: 7472-7482 |
Kelly TJ, Bonniwell EM, Mu L, et al. (2023) Psilocybin analog 4-OH-DiPT enhances fear extinction and GABAergic inhibition of principal neurons in the basolateral amygdala. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology |
Wallach J, Cao AB, Calkins MM, et al. (2023) Identification of 5-HT Receptor Signaling Pathways Responsible for Psychedelic Potential. Biorxiv : the Preprint Server For Biology |
Tosh DK, Calkins MM, Ivancich MS, et al. (2023) Structure activity relationships of 5-HT and 5-HT serotonin receptor antagonists: N, C2 and 5'-Modified (N)-methanocarba-adenosine derivatives. European Journal of Medicinal Chemistry. 259: 115691 |
Malcolm NJ, Palkovic B, Sprague DJ, et al. (2023) Mu-opioid receptor selective superagonists produce prolonged respiratory depression. Iscience. 26: 107121 |
Lewis V, Bonniwell EM, Lanham JK, et al. (2023) A non-hallucinogenic LSD analog with therapeutic potential for mood disorders. Cell Reports. 42: 112203 |
Vargas MV, Dunlap LE, Dong C, et al. (2023) Psychedelics promote neuroplasticity through the activation of intracellular 5-HT2A receptors. Science (New York, N.Y.). 379: 700-706 |
Yahya NA, Lanham JK, Sprague DJ, et al. (2023) Molecular and cellular basis of praziquantel action in the cardiovascular system. American Journal of Physiology. Cell Physiology |