Jun Shen, Ph.D.

Harvard University, Cambridge, MA, United States 
Genes involved in the development and function of the cerebral cortex
"Jun Shen"
Mean distance: 14.84 (cluster 46)


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Chris A. Walsh grad student 2005 Harvard
 (Using forward and reverse genetics to study genes that control the size of the brain.)
David P. Corey post-doc 2003-2012 Harvard Medical School
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Evrony GD, Cordero DR, Shen J, et al. (2017) Integrated genome and transcriptome sequencing identifies a noncoding mutation in the genome replication factor DONSON as the cause of microcephaly-micromelia syndrome. Genome Research
Lin SY, Vollrath MA, Mangosing S, et al. (2015) The zebrafish pinball wizard gene encodes WRB, a tail-anchored-protein receptor essential for inner-ear hair cells and retinal photoreceptors. The Journal of Physiology
Shen J, Scheffer DI, Kwan KY, et al. (2015) SHIELD: an integrative gene expression database for inner ear research. Database : the Journal of Biological Databases and Curation. 2015: bav071
Scheffer DI, Shen J, Corey DP, et al. (2015) Gene Expression by Mouse Inner Ear Hair Cells during Development. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 6366-80
Scheffer DI, Zhang DS, Shen J, et al. (2015) XIRP2, an actin-binding protein essential for inner ear hair-cell stereocilia. Cell Reports. 10: 1811-8
Kwan KY, Shen J, Corey DP. (2015) C-MYC transcriptionally amplifies SOX2 target genes to regulate self-renewal in multipotent otic progenitor cells. Stem Cell Reports. 4: 47-60
Shen J, Gilmore EC, Marshall CA, et al. (2010) Mutations in PNKP cause microcephaly, seizures and defects in DNA repair. Nature Genetics. 42: 245-9
Powers SE, Taniguchi K, Yen W, et al. (2010) Tgif1 and Tgif2 regulate Nodal signaling and are required for gastrulation. Development (Cambridge, England). 137: 249-59
Shen J, Eyaid W, Mochida GH, et al. (2005) ASPM mutations identified in patients with primary microcephaly and seizures. Journal of Medical Genetics. 42: 725-9
Shen J, Walsh CA. (2005) Targeted disruption of Tgif, the mouse ortholog of a human holoprosencephaly gene, does not result in holoprosencephaly in mice. Molecular and Cellular Biology. 25: 3639-47
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