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Philip Leder

Affiliations: 
Harvard Medical School, Boston, MA, United States 
Area:
Genetics
Website:
http://www.dfhcc.harvard.edu/insider/member-detail/member/philip-leder-md/
Google:
"Philip Leder"
Bio:

http://www.nasonline.org/member-directory/members/53399.html
http://www.asbmb.org/asbmbtoday/201202/Features/Leder/

Mean distance: 14.76 (cluster 11)
 		SNBCP
Cross-listing: GenetiTree

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Parents

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Marshall Nirenberg post-doc 1962 NIH

Children

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Jonathan Seidman grad student NIH (GenetiTree)
Philip Hieter grad student 1981 Johns Hopkins (Microtree)
Philip N. Benfey grad student 1986 Harvard (Plant Biology Tree)
Laurie Jackson-Grusby grad student 1987-1992 Harvard Medical School
Hsiuchen Chen grad student 2000 Harvard
Edward Jay Weinstein grad student 2000 Harvard
Robert Jon Monroe grad student 2001 Harvard
Benjamin Simon Leader grad student 2003 Harvard
David R. Beier post-doc Harvard Medical School
Nancy Berliner post-doc Harvard Medical School
Alexander J Bishop post-doc Harvard Medical School (Cell Biology Tree)
John Flanagan post-doc HMS
Stanley J. Korsmeyer post-doc NIH (Cell Biology Tree)
Timothy J. Ley post-doc NIH (Cell Biology Tree)
David M. Livingston post-doc
Richard L. Maas post-doc Harvard Medical School (Microtree)
Stuart S. Martin post-doc (Cell Biology Tree)
Stuart H. Orkin post-doc NIH
Randall R. Reed post-doc Harvard Medical School
Rick Woychik post-doc Harvard Medical School (Cell Biology Tree)
Tasuku Honjo post-doc 1973-1974 NIH
Jianrong Lu post-doc 2005 Harvard Medical School (Chemistry Tree)

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Publications

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Caskey CT, Leder P. (2014) The RNA code: nature's Rosetta Stone. Proceedings of the National Academy of Sciences of the United States of America. 111: 5758-9
Ravi D, Wiles AM, Bhavani S, et al. (2009) A network of conserved damage survival pathways revealed by a genomic RNAi screen. Plos Genetics. 5: e1000527
Zhou F, Leder P, Zuniga A, et al. (2009) Formin1 disruption confers oligodactylism and alters Bmp signaling. Human Molecular Genetics. 18: 2472-82
Babbe H, McMenamin J, Hobeika E, et al. (2009) Genomic instability resulting from Blm deficiency compromises development, maintenance, and function of the B cell lineage. Journal of Immunology (Baltimore, Md. : 1950). 182: 347-60
Dettenhofer M, Zhou F, Leder P. (2008) Formin 1-isoform IV deficient cells exhibit defects in cell spreading and focal adhesion formation. Plos One. 3: e2497
Leder A, McMenamin J, Zhou F, et al. (2008) Genome-wide SNP analysis of Tg.AC transgenic mice reveals an oncogenic collaboration between v-Ha-ras and Ink4a, which is absent in p53 deficiency. Oncogene. 27: 2456-65
Li X, Leder P. (2007) Identifying genes preferentially expressed in undifferentiated embryonic stem cells. Bmc Cell Biology. 8: 37
Lu J, Ruhf ML, Perrimon N, et al. (2007) A genome-wide RNA interference screen identifies putative chromatin regulators essential for E2F repression. Proceedings of the National Academy of Sciences of the United States of America. 104: 9381-6
Babbe H, Chester N, Leder P, et al. (2007) The Bloom's syndrome helicase is critical for development and function of the alphabeta T-cell lineage. Molecular and Cellular Biology. 27: 1947-59
Chester N, Babbe H, Pinkas J, et al. (2006) Mutation of the murine Bloom's syndrome gene produces global genome destabilization. Molecular and Cellular Biology. 26: 6713-26
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