Alicia M. Ruggiero, Ph.D.

Affiliations: 
Johns Hopkins University, Baltimore, MD 
Area:
Transporter, ALS
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"Alicia Ruggiero"
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Jeffrey D. Rothstein grad student 2005 Johns Hopkins
 (Regulation of excitatory amino acid transporters by the associated protein GTRAP3-18.)
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Publications

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Barwick KE, Wright J, Al-Turki S, et al. (2012) Defective presynaptic choline transport underlies hereditary motor neuropathy. American Journal of Human Genetics. 91: 1103-7
Ruggiero AM, Wright J, Ferguson SM, et al. (2012) Nonoisotopic assay for the presynaptic choline transporter reveals capacity for allosteric modulation of choline uptake. Acs Chemical Neuroscience. 3: 767-81
Veenstra-VanderWeele J, Xu T, Ruggiero AM, et al. (2012) Functional studies and rare variant screening of SLC1A1/EAAC1 in males with obsessive-compulsive disorder. Psychiatric Genetics. 22: 256-60
Lund D, Ruggiero AM, Ferguson SM, et al. (2010) Motor neuron-specific overexpression of the presynaptic choline transporter: impact on motor endurance and evoked muscle activity. Neuroscience. 171: 1041-53
English BA, Appalsamy M, Diedrich A, et al. (2010) Tachycardia, reduced vagal capacity, and age-dependent ventricular dysfunction arising from diminished expression of the presynaptic choline transporter. American Journal of Physiology. Heart and Circulatory Physiology. 299: H799-810
Maier S, Reiterer V, Ruggiero AM, et al. (2009) GTRAP3-18 serves as a negative regulator of Rab1 in protein transport and neuronal differentiation. Journal of Cellular and Molecular Medicine. 13: 114-24
Misawa H, Fujigaya H, Nishimura T, et al. (2008) Aberrant trafficking of the high-affinity choline transporter in AP-3-deficient mice. The European Journal of Neuroscience. 27: 3109-17
Ruggiero AM, Liu Y, Vidensky S, et al. (2008) The endoplasmic reticulum exit of glutamate transporter is regulated by the inducible mammalian Yip6b/GTRAP3-18 protein. The Journal of Biological Chemistry. 283: 6175-83
Liu Y, Vidensky S, Ruggiero AM, et al. (2008) Reticulon RTN2B regulates trafficking and function of neuronal glutamate transporter EAAC1. The Journal of Biological Chemistry. 283: 6561-71
Lin CI, Orlov I, Ruggiero AM, et al. (2001) Modulation of the neuronal glutamate transporter EAAC1 by the interacting protein GTRAP3-18. Nature. 410: 84-8
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