Leon G. Coleman, Ph.D.

Affiliations: 
Neurobiology University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Alcoholism
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"Leon Coleman"
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Fulton T. Crews grad student 2010 UNC Chapel Hill
 (The long-term effects of adolescent and postnatal ethanol exposure on the adult mouse brain: A multidisciplinary approach.)
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Publications

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McMahan RH, Anton P, Coleman LG, et al. (2023) Alcohol and Immunology: Mechanisms of Multi-Organ Damage. Summary of the 2022 Alcohol and Immunology Research Interest Group (AIRIG) meeting. Alcohol (Fayetteville, N.Y.)
Crews FT, Coleman LG, Macht VA, et al. (2022) Targeting Persistent Changes in Neuroimmune and Epigenetic Signaling in Adolescent Drinking to Treat Alcohol Use Disorder in Adulthood. Pharmacological Reviews. 75: 380-396
Crotty K, Anton P, Coleman LG, et al. (2022) A critical review of recent knowledge of alcohol's effects on the immunological response in different tissues. Alcoholism, Clinical and Experimental Research
Zou J, Walter TJ, Barnett A, et al. (2022) Ethanol Induces Secretion of Proinflammatory Extracellular Vesicles That Inhibit Adult Hippocampal Neurogenesis Through G9a/GLP-Epigenetic Signaling. Frontiers in Immunology. 13: 866073
Barnett A, David E, Rohlman A, et al. (2022) Adolescent Binge Alcohol Enhances Early Alzheimer's Disease Pathology in Adulthood Through Proinflammatory Neuroimmune Activation. Frontiers in Pharmacology. 13: 884170
Coleman LG, Crews FT, Vetreno RP. (2021) The persistent impact of adolescent binge alcohol on adult brain structural, cellular, and behavioral pathology: A role for the neuroimmune system and epigenetics. International Review of Neurobiology. 160: 1-44
Vetreno RP, Qin L, Coleman LG, et al. (2021) Increased Toll-like Receptor-MyD88-NFκB-Proinflammatory neuroimmune signaling in the orbitofrontal cortex of human alcohol use disorder. Alcoholism, Clinical and Experimental Research
Qin L, Zou J, Barnett A, et al. (2021) TRAIL Mediates Neuronal Death in AUD: A Link between Neuroinflammation and Neurodegeneration. International Journal of Molecular Sciences. 22
Crews FT, Zou J, Coleman LG. (2021) Extracellular microvesicles promote microglia-mediated pro-inflammatory responses to ethanol. Journal of Neuroscience Research
Barnett AM, Crews FT, Coleman LG. (2021) Microglial depletion and repopulation: a new era of regenerative medicine? Neural Regeneration Research. 16: 1204-1205
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