Christopher R. Campos, Ph.D.

Affiliations: 
Medical Pharmacology University of Arizona, Tucson, AZ 
Area:
blood-brain barrier, drug delivery
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Parents

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Thomas P. Davis grad student 2009 University of Arizona
 (Central regulation of blood-brain barrier integrity during hyperalgesia.)
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Publications

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Campos CR, Kemble AM, Niewoehner J, et al. (2020) Brain Shuttle Neprilysin reduces central Amyloid-β levels. Plos One. 15: e0229850
More VR, Campos CR, Evans RA, et al. (2016) PPAR-α, a lipid-sensing transcription factor, regulates blood-brain barrier efflux transporter expression. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism
Wang X, Campos CR, Peart JC, et al. (2014) Nrf2 upregulates ATP binding cassette transporter expression and activity at the blood-brain and blood-spinal cord barriers. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 8585-93
Bartels K, Ma Q, Venkatraman TN, et al. (2014) Effects of deep hypothermic circulatory arrest on the blood brain barrier in a cardiopulmonary bypass model--a pilot study. Heart, Lung & Circulation. 23: 981-4
Emmert D, Campos CR, Ward D, et al. (2014) Reversible dimers of the atypical antipsychotic quetiapine inhibit p-glycoprotein-mediated efflux in vitro with increased binding affinity and in situ at the blood-brain barrier. Acs Chemical Neuroscience. 5: 305-17
Largent-Milnes TM, Brookshire SW, Skinner DP, et al. (2013) Building a better analgesic: multifunctional compounds that address injury-induced pathology to enhance analgesic efficacy while eliminating unwanted side effects. The Journal of Pharmacology and Experimental Therapeutics. 347: 7-19
Cartwright TA, Campos CR, Cannon RE, et al. (2013) Mrp1 is essential for sphingolipid signaling to p-glycoprotein in mouse blood-brain and blood-spinal cord barriers. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 33: 381-8
Durk MR, Chan GN, Campos CR, et al. (2012) 1α,25-Dihydroxyvitamin D3-liganded vitamin D receptor increases expression and transport activity of P-glycoprotein in isolated rat brain capillaries and human and rat brain microvessel endothelial cells. Journal of Neurochemistry. 123: 944-53
Cannon RE, Peart JC, Hawkins BT, et al. (2012) Targeting blood-brain barrier sphingolipid signaling reduces basal P-glycoprotein activity and improves drug delivery to the brain. Proceedings of the National Academy of Sciences of the United States of America. 109: 15930-5
Jablonski MR, Jacob DA, Campos C, et al. (2012) Selective increase of two ABC drug efflux transporters at the blood-spinal cord barrier suggests induced pharmacoresistance in ALS. Neurobiology of Disease. 47: 194-200
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