Samir Koirala, Ph.D.

Affiliations: 
1996-2002 University of Southern California, Los Angeles, CA, United States 
 2003-2010 Children's Hospital and Harvard Medical School, Boston, MA, United States 
 2011-2017 Amgen Inc., Thousand Oaks, CA, United States 
 2017- Biogen, Morrisville, NC, United States 
Area:
Alzheimer's Disease, Angelman Syndrome, Neurodevelopmental Disorders, Brain Development, Cerebellum, Polymicrogyria, Neuroinflammation, Schwann cells, Neuromuscular junction, Synapse Development, Nerve Regeneration, Peripheral Neuropathy, Neuropathic Pain
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Chien-Ping Ko grad student 2002 USC
 (The role of perisynaptic glial cells in synapse formation, maintenance, and regeneration.)
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Publications

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Puram SV, Riccio A, Koirala S, et al. (2011) A TRPC5-regulated calcium signaling pathway controls dendrite patterning in the mammalian brain. Genes & Development. 25: 2659-73
Koirala S, Corfas G. (2010) Identification of novel glial genes by single-cell transcriptional profiling of Bergmann glial cells from mouse cerebellum. Plos One. 5: e9198
Koirala S, Jin Z, Piao X, et al. (2009) GPR56-regulated granule cell adhesion is essential for rostral cerebellar development. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 7439-49
Li S, Jin Z, Koirala S, et al. (2008) GPR56 regulates pial basement membrane integrity and cortical lamination. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 5817-26
Wu A, Koirala S, Corfas G, et al. (2008) Examining the role of neuregulin-1 in synaptogenesis using microfluidics 12th International Conference On Miniaturized Systems For Chemistry and Life Sciences - the Proceedings of Microtas 2008 Conference. 1840-1842
Sardi SP, Murtie J, Koirala S, et al. (2006) Presenilin-dependent ErbB4 nuclear signaling regulates the timing of astrogenesis in the developing brain. Cell. 127: 185-97
Patten BA, Sardi SP, Koirala S, et al. (2006) Notch1 signaling regulates radial glia differentiation through multiple transcriptional mechanisms. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 3102-8
Feng Z, Koirala S, Ko CP. (2005) Synapse-glia interactions at the vertebrate neuromuscular junction. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. 11: 503-13
Koirala S, Ko CP. (2004) Pruning an axon piece by piece: a new mode of synapse elimination. Neuron. 44: 578-80
Koirala S, Reddy LV, Ko CP. (2003) Roles of glial cells in the formation, function, and maintenance of the neuromuscular junction. Journal of Neurocytology. 32: 987-1002
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