Zhihua Feng, Ph.D.

Affiliations: 
Biology: Doctor of Philosophy University of Southern California, Los Angeles, CA, United States 
Area:
Schwann cells, Neuromuscular junctions
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"Zhihua Feng"
Mean distance: 16.27 (cluster 6)
 
SNBCP

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Chien-Ping Ko grad student 2007 USC
 (The role of Schwann cells in the formation of the neuromuscular junction.)
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Publications

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Miller N, Xu Z, Quinlan KA, et al. (2023) Mitigating aberrant Cdk5 activation alleviates mitochondrial defects and motor neuron disease symptoms in spinal muscular atrophy. Proceedings of the National Academy of Sciences of the United States of America. 120: e2300308120
Kim JK, Jha NN, Awano T, et al. (2023) A spinal muscular atrophy modifier implicates the SMN protein in SNARE complex assembly at neuromuscular synapses. Neuron
Zhao X, Feng Z, Risher N, et al. (2021) SMN protein is required throughout life to prevent spinal muscular atrophy disease progression. Human Molecular Genetics
Feng Z, Lam S, Tenn ES, et al. (2021) Activation of Muscle-Specific Kinase (MuSK) Reduces Neuromuscular Defects in the Delta7 Mouse Model of Spinal Muscular Atrophy (SMA). International Journal of Molecular Sciences. 22
Feng Z, Ling KKY, Zhao X, et al. (2020) Corrigendum to: Pharmacologically-induced mouse model of adult spinal muscular atrophy to evaluate effectiveness of therapeutics after disease onset. Human Molecular Genetics
Osman EY, Van Alstyne M, Yen PF, et al. (2020) Minor snRNA gene delivery improves the loss of proprioceptive synapses on SMA motor neurons. Jci Insight
Kim JK, Jha NN, Feng Z, et al. (2020) Muscle-specific SMN reduction reveals motor neuron-independent disease in spinal muscular atrophy models. The Journal of Clinical Investigation
Rimer M, Seaberg BL, Yen PF, et al. (2019) Nerve sprouting capacity in a pharmacologically induced mouse model of spinal muscular atrophy. Scientific Reports. 9: 7799
Ratni H, Ebeling M, Baird J, et al. (2018) Discovery of Risdiplam, a Selective Survival of Motor Neuron-2 ( SMN2) Gene Splicing Modifier for the Treatment of Spinal Muscular Atrophy (SMA). Journal of Medicinal Chemistry
Zhao X, Feng Z, Ling KK, et al. (2016) Pharmacokinetics, Pharmacodynamics and Efficacy of a Small Molecule SMN2 Splicing Modifier in Mouse Models of Spinal Muscular Atrophy. Human Molecular Genetics
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