Alexander R. McCampbell, Ph.D.

Affiliations: 
University of Pennsylvania, Philadelphia, PA, United States 
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"Alexander McCampbell"
Mean distance: 18.31 (cluster 11)
 
SNBCP

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Kenneth H. Fischbeck grad student 2001 Penn
 (Transcriptional co -activator dysfunction in polyglutamine disease.)
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Publications

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Staropoli JF, Li H, Chun SJ, et al. (2015) Rescue of gene-expression changes in an induced mouse model of spinal muscular atrophy by an antisense oligonucleotide that promotes inclusion of SMN2 exon 7. Genomics. 105: 220-8
Converso A, Hartingh T, Fraley ME, et al. (2014) Adenosine analogue inhibitors of S-adenosylhomocysteine hydrolase. Bioorganic & Medicinal Chemistry Letters. 24: 2737-40
Savage MJ, Kalinina J, Wolfe A, et al. (2014) A sensitive aβ oligomer assay discriminates Alzheimer's and aged control cerebrospinal fluid. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 2884-97
Zhao WQ, Toolan D, Hepler RW, et al. (2011) High throughput monitoring of amyloid-β(42) assembly into soluble oligomers achieved by sensitive conformation state-dependent immunoassays. Journal of Alzheimer's Disease : Jad. 25: 655-69
McCampbell A, Wessner K, Marlatt MW, et al. (2011) Induction of Alzheimer's-like changes in brain of mice expressing mutant APP fed excess methionine. Journal of Neurochemistry. 116: 82-92
Eichler FS, Hornemann T, McCampbell A, et al. (2009) Overexpression of the wild-type SPT1 subunit lowers desoxysphingolipid levels and rescues the phenotype of HSAN1. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 14646-51
Ma L, Seager MA, Seager M, et al. (2009) Selective activation of the M1 muscarinic acetylcholine receptor achieved by allosteric potentiation. Proceedings of the National Academy of Sciences of the United States of America. 106: 15950-5
McCampbell A, Truong D, Broom DC, et al. (2005) Mutant SPTLC1 dominantly inhibits serine palmitoyltransferase activity in vivo and confers an age-dependent neuropathy. Human Molecular Genetics. 14: 3507-21
McCampbell A, Taye AA, Whitty L, et al. (2001) Histone deacetylase inhibitors reduce polyglutamine toxicity. Proceedings of the National Academy of Sciences of the United States of America. 98: 15179-84
Steffan JS, Bodai L, Pallos J, et al. (2001) Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila. Nature. 413: 739-43
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