Kurt Laha, Ph.D.

Affiliations: 
Biological Sciences Marquette University, Milwaukee, WI, United States 
Area:
GABA(A) receptor structure-function; GABA(A) receptor kinetics
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"Kurt Laha"
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David Wagner grad student 2011 Marquette University
 (Exploring the architecture of the human GABA(A) receptor ligand binding pocket via mutational, electrophysiological, and kinetic analysis.)
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Publications

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Zarnowska ED, Rodgers FC, Oh I, et al. (2015) Etomidate blocks LTP and impairs learning but does not enhance tonic inhibition in mice carrying the N265M point mutation in the beta3 subunit of the GABA(A) receptor. Neuropharmacology. 93: 171-8
Laha KT, Ghosh B, Czajkowski C. (2013) Macroscopic kinetics of pentameric ligand gated ion channels: comparisons between two prokaryotic channels and one eukaryotic channel. Plos One. 8: e80322
Laha KT, Tran PN. (2013) Multiple tyrosine residues at the GABA binding pocket influence surface expression and mediate kinetics of the GABAA receptor. Journal of Neurochemistry. 124: 200-9
Tran PN, Laha KT, Wagner DA. (2011) A tight coupling between β₂Y97 and β₂F200 of the GABA(A) receptor mediates GABA binding. Journal of Neurochemistry. 119: 283-93
Laha KT, Wagner DA. (2011) A state-dependent salt-bridge interaction exists across the β/α intersubunit interface of the GABAA receptor. Molecular Pharmacology. 79: 662-71
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