Layla Azam, Ph.D.

Affiliations: 
University of California, Irvine, Irvine, CA 
Area:
Brain development, drug abuse, nicotine
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"Layla Azam"
Mean distance: 17.04 (cluster 41)
 
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Parents

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Frances M. Leslie grad student 2001 UC Irvine
 (Characterization of nicotinic acetylcholine receptors within rat brain monoaminergic neurons.)
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Publications

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Rybin MJ, O'Brien H, Ramiro IBL, et al. (2020) αM-Conotoxin MIIIJ Blocks Nicotinic Acetylcholine Receptors at Neuromuscular Junctions of Frog and Fish. Toxins. 12
Zhang MM, Wilson MJ, Azam L, et al. (2013) Co-expression of Na(V)β subunits alters the kinetics of inhibition of voltage-gated sodium channels by pore-blocking μ-conotoxins. British Journal of Pharmacology. 168: 1597-610
Azam L, McIntosh JM. (2012) Molecular basis for the differential sensitivity of rat and human α9α10 nAChRs to α-conotoxin RgIA. Journal of Neurochemistry. 122: 1137-44
Azam L, Maskos U, Changeux JP, et al. (2010) α-Conotoxin BuIA[T5A;P6O]: a novel ligand that discriminates between α6ß4 and α6ß2 nicotinic acetylcholine receptors and blocks nicotine-stimulated norepinephrine release. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 5113-23
Azam L, McIntosh JM. (2009) Alpha-conotoxins as pharmacological probes of nicotinic acetylcholine receptors. Acta Pharmacologica Sinica. 30: 771-83
Azam L, Yoshikami D, McIntosh JM. (2008) Amino acid residues that confer high selectivity of the alpha6 nicotinic acetylcholine receptor subunit to alpha-conotoxin MII[S4A,E11A,L15A]. The Journal of Biological Chemistry. 283: 11625-32
Azam L, Chen Y, Leslie FM. (2007) Developmental regulation of nicotinic acetylcholine receptors within midbrain dopamine neurons. Neuroscience. 144: 1347-60
Azam L, McIntosh JM. (2006) Characterization of nicotinic acetylcholine receptors that modulate nicotine-evoked [3H]norepinephrine release from mouse hippocampal synaptosomes. Molecular Pharmacology. 70: 967-76
Azam L, Dowell C, Watkins M, et al. (2005) Alpha-conotoxin BuIA, a novel peptide from Conus bullatus, distinguishes among neuronal nicotinic acetylcholine receptors. The Journal of Biological Chemistry. 280: 80-7
Azam L, McIntosh JM. (2005) Effect of novel alpha-conotoxins on nicotine-stimulated [3H]dopamine release from rat striatal synaptosomes. The Journal of Pharmacology and Experimental Therapeutics. 312: 231-7
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