Audrey S. Dickey, Ph.D.

Affiliations: 
2017- Neurology Duke University School of Medicine, Durham, NC, United States 
Area:
protein phosphatases, mitochondria, Omics, transcriptome, transcription, autophagy, inflammation, preclinical trial, iPSCs
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"Audrey Dickey"
Mean distance: 15.77 (cluster 6)
 
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Stefan Strack grad student 2010 University of Iowa
 (Role of PP2A/Bbeta2 and PKA/AKAP1 in brain development and function via dynamin-related protein 1 (Drp1) control of mitochondria shape and bioenergetics.)
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Publications

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Flippo KH, Lin Z, Dickey AS, et al. (2020) Deletion of a neuronal Drp1 activator protects against cerebral ischemia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience
Gao R, Chakraborty A, Geater C, et al. (2019) Mutant huntingtin impairs PNKP and ATXN3, disrupting DNA repair and transcription. Elife. 8
Flippo KH, Gnanasekaran A, Perkins GA, et al. (2018) AKAP1 protects from cerebral ischemic stroke by inhibiting Drp1-dependent mitochondrial fission. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience
Mihaylova MM, Cheng CW, Cao AQ, et al. (2018) Fasting Activates Fatty Acid Oxidation to Enhance Intestinal Stem Cell Function during Homeostasis and Aging. Cell Stem Cell. 22: 769-778.e4
Dickey AS, La Spada AR. (2017) Therapy development in Huntington disease: From current strategies to emerging opportunities. American Journal of Medical Genetics. Part A
Dickey AS, Sanchez DN, Arreola M, et al. (2017) PPARδ activation by bexarotene promotes neuroprotection by restoring bioenergetic and quality control homeostasis. Science Translational Medicine. 9
Dickey AS, Pineda VV, Tsunemi T, et al. (2015) PPAR-δ is repressed in Huntington's disease, is required for normal neuronal function and can be targeted therapeutically. Nature Medicine
Dickey AS, Strack S. (2011) PKA/AKAP1 and PP2A/Bβ2 regulate neuronal morphogenesis via Drp1 phosphorylation and mitochondrial bioenergetics. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 15716-26
Merrill RA, Dagda RK, Dickey AS, et al. (2011) Mechanism of neuroprotective mitochondrial remodeling by PKA/AKAP1. Plos Biology. 9: e1000612
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