Yan Ling, Ph.D.
Affiliations: | University of North Carolina, Chapel Hill, Chapel Hill, NC |
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"Yan Ling"Mean distance: 19.15 (cluster 11)
Parents
Sign in to add mentor| Kay Lund | grad student | 2000 | UNC Chapel Hill | |
| (Role of insulin receptor substrate 1 (IRS -1) in mediating normal and insulin -like growth factor I (IGF -I) dependent bowel growth in vivo.) | ||||
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Publications
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| Radhakrishnan Y, Maile LA, Ling Y, et al. (2008) Insulin-like growth factor-I stimulates Shc-dependent phosphatidylinositol 3-kinase activation via Grb2-associated p85 in vascular smooth muscle cells Journal of Biological Chemistry. 283: 16320-16331 |
| Clemmons DR, Maile LA, Ling Y, et al. (2007) Role of the integrin αVβ3 in mediating increased smooth muscle cell responsiveness to IGF-I in response to hyperglycemic stress Growth Hormone & Igf Research. 17: 265-270 |
| Maile LA, Capps BE, Ling Y, et al. (2007) Hyperglycemia Alters the Responsiveness of Smooth Muscle Cells to Insulin-Like Growth Factor-I Endocrinology. 148: 2435-2443 |
| Lieskovska J, Ling Y, Badley-Clarke J, et al. (2006) The role of Src kinase in insulin-like growth factor-dependent mitogenic signaling in vascular smooth muscle cells. Journal of Biological Chemistry. 281: 25041-25053 |
| Kwon M, Ling Y, Maile LA, et al. (2006) Recruitment of the tyrosine phosphatase Src homology 2 domain tyrosine phosphatase-2 to the p85 subunit of phosphatidylinositol-3 (PI-3) kinase is required for insulin-like growth factor-I-dependent PI-3 kinase activation in smooth muscle cells. Endocrinology. 147: 1458-1465 |
| Ling Y, Maile LA, Lieskovska J, et al. (2005) Role of SHPS-1 in the regulation of insulin-like growth factor I-stimulated Shc and mitogen-activated protein kinase activation in vascular smooth muscle cells. Molecular Biology of the Cell. 16: 3353-3364 |
| Ling Y, Maile LA, Badley-Clarke J, et al. (2005) DOK1 Mediates SHP-2 Binding to the αVβ3 Integrin and Thereby Regulates Insulin-like Growth Factor I Signaling in Cultured Vascular Smooth Muscle Cells Journal of Biological Chemistry. 280: 3151-3158 |
| Ling Y, Maile LA, Clemmons DR. (2003) Tyrosine Phosphorylation of the β3-Subunit of the αVβ3 Integrin Is Required for Membrane Association of the Tyrosine Phosphatase SHP-2 and Its Further Recruitment to the Insulin-Like Growth Factor I Receptor Molecular Endocrinology. 17: 1824-1833 |