Margaret J. VanDoren, Ph.D.

Affiliations: 
University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Alcohol, GABA, neurosteroids
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"Margaret VanDoren"
Mean distance: 17.98 (cluster 11)
 
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A Leslie Morrow grad student 2001 UNC Chapel Hill
 (The role of 3alpha-hydroxy-5alpha-pregnan-20-one in ethanol action in the brain.)
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Publications

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Marx CE, Shampine LJ, Duncan GE, et al. (2006) Clozapine markedly elevates pregnenolone in rat hippocampus, cerebral cortex, and serum: candidate mechanism for superior efficacy? Pharmacology, Biochemistry, and Behavior. 84: 598-608
Grobin AC, VanDoren MJ, Porrino LJ, et al. (2005) Cortical 3 alpha-hydroxy-5 alpha-pregnan-20-one levels after acute administration of Delta 9-tetrahydrocannabinol, cocaine and morphine. Psychopharmacology. 179: 544-50
Khisti RT, VanDoren MJ, Matthews DB, et al. (2004) Ethanol-induced elevation of 3 alpha-hydroxy-5 alpha-pregnan-20-one does not modulate motor incoordination in rats. Alcoholism, Clinical and Experimental Research. 28: 1249-56
Khisti RT, VanDoren MJ, O'Buckley T, et al. (2003) Neuroactive steroid 3 alpha-hydroxy-5 alpha-pregnan-20-one modulates ethanol-induced loss of righting reflex in rats. Brain Research. 980: 255-65
Marx CE, VanDoren MJ, Duncan GE, et al. (2003) Olanzapine and clozapine increase the GABAergic neuroactive steroid allopregnanolone in rodents. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 28: 1-13
Khisti RT, Penland SN, VanDoren MJ, et al. (2002) GABAergic neurosteroid modulation of ethanol actions. The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry. 3: 87-95
Mihalek RM, Bowers BJ, Wehner JM, et al. (2001) GABA(A)-receptor delta subunit knockout mice have multiple defects in behavioral responses to ethanol. Alcoholism, Clinical and Experimental Research. 25: 1708-18
Morrow AL, VanDoren MJ, Penland SN, et al. (2001) The role of GABAergic neuroactive steroids in ethanol action, tolerance and dependence. Brain Research. Brain Research Reviews. 37: 98-109
Morrow AL, VanDoren MJ, Fleming R, et al. (2001) Ethanol and neurosteroid interactions in the brain. International Review of Neurobiology. 46: 349-77
VanDoren MJ, Matthews DB, Janis GC, et al. (2000) Neuroactive steroid 3alpha-hydroxy-5alpha-pregnan-20-one modulates electrophysiological and behavioral actions of ethanol. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 1982-9
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