Xiaojie Li, Ph.D.
Affiliations: | Johns Hopkins University, Baltimore, MD |
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"Xiaojie Li"Mean distance: 15.97 (cluster 56) | S | N | B | C | P |
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Sign in to add mentor| Ted M. Dawson | grad student | 2010 | Johns Hopkins | |
| (Phosphorylation of Parkinson's disease associated leucine-rich repeat kinase 2 (LRRK2) protein Development and Characterization of specific anti-LRRK2 antibodies.) | ||||
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Publications
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| Lee BD, Li X, Dawson TM, et al. (2012) Measuring the activity of leucine-rich repeat kinase 2: a kinase involved in Parkinson's disease. Methods in Molecular Biology (Clifton, N.J.). 795: 45-54 |
| Li X, Moore DJ, Xiong Y, et al. (2010) Reevaluation of phosphorylation sites in the Parkinson disease-associated leucine-rich repeat kinase 2. The Journal of Biological Chemistry. 285: 29569-76 |
| Xiong Y, Coombes CE, Kilaru A, et al. (2010) GTPase activity plays a key role in the pathobiology of LRRK2. Plos Genetics. 6: e1000902 |
| Andres-Mateos E, Mejias R, Sasaki M, et al. (2009) Unexpected lack of hypersensitivity in LRRK2 knock-out mice to MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine). The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 15846-50 |
| Waxman EA, Covy JP, Bukh I, et al. (2009) Leucine-rich repeat kinase 2 expression leads to aggresome formation that is not associated with alpha-synuclein inclusions. Journal of Neuropathology and Experimental Neurology. 68: 785-96 |
| West AB, Moore DJ, Choi C, et al. (2007) Parkinson's disease-associated mutations in LRRK2 link enhanced GTP-binding and kinase activities to neuronal toxicity. Human Molecular Genetics. 16: 223-32 |
| Sriram SR, Li X, Ko HS, et al. (2005) Familial-associated mutations differentially disrupt the solubility, localization, binding and ubiquitination properties of parkin. Human Molecular Genetics. 14: 2571-86 |
| Smith WW, Margolis RL, Li X, et al. (2005) Alpha-synuclein phosphorylation enhances eosinophilic cytoplasmic inclusion formation in SH-SY5Y cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 5544-52 |
| Chung KK, Thomas B, Li X, et al. (2004) S-nitrosylation of parkin regulates ubiquitination and compromises parkin's protective function. Science (New York, N.Y.). 304: 1328-31 |