Andrei V. Karginov, Ph.D.

University of Virginia, Charlottesville, VA 
Signal transduction
"Andrei Karginov"
Mean distance: 19.45 (cluster 11)


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J. Thomas Parsons grad student 2005 UVA
 (Involvement of cortactin in regulation of the actin cytoskeleton and endocytosis.)
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Zimnicka AM, Husain YS, Shajahan AN, et al. (2016) Src-dependent phosphorylation of caveolin-1 Tyr14 promotes swelling and release of caveolae. Molecular Biology of the Cell
Gentry LR, Karginov AV, Hahn KM, et al. (2016) Characterization of an engineered Src kinase to study Src signaling and biology Methods in Molecular Biology. 1360: 157-167
Shen B, Estevez B, Xu Z, et al. (2015) The interaction of Gα13 with integrin β1 mediates cell migration by dynamic regulation of RhoA. Molecular Biology of the Cell
Wang L, Burmeister BT, Johnson KR, et al. (2015) UCR1C is a novel activator of phosphodiesterase 4 (PDE4) long isoforms and attenuates cardiomyocyte hypertrophy. Cellular Signalling. 27: 908-22
Chu PH, Tsygankov D, Berginski ME, et al. (2014) Engineered kinase activation reveals unique morphodynamic phenotypes and associated trafficking for Src family isoforms. Proceedings of the National Academy of Sciences of the United States of America. 111: 12420-5
Patel M, Kawano T, Suzuki N, et al. (2014) Gα13/PDZ-RhoGEF/RhoA signaling is essential for gastrin-releasing peptide receptor-mediated colon cancer cell migration. Molecular Pharmacology. 86: 252-62
Karginov AV, Hahn KM, Deiters A. (2014) Optochemical activation of kinase function in live cells. Methods in Molecular Biology (Clifton, N.J.). 1148: 31-43
Karginov AV, Tsygankov D, Berginski M, et al. (2014) Dissecting motility signaling through activation of specific Src-effector complexes. Nature Chemical Biology. 10: 286-90
Patel M, Karginov AV. (2014) Phosphorylation-mediated regulation of GEFs for RhoA. Cell Adhesion & Migration. 8: 11-8
Dagliyan O, Shirvanyants D, Karginov AV, et al. (2013) Rational design of a ligand-controlled protein conformational switch. Proceedings of the National Academy of Sciences of the United States of America. 110: 6800-4
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