Christopher E. Hart, Ph.D.

Affiliations: 
California Institute of Technology, Pasadena, CA 
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"Christopher Hart"
Mean distance: 15.49 (cluster 11)
 
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Barbara  J. Wold grad student 2005 Caltech
 (Inferring genetic regulatory network structure: Integrative analysis of genome -scale data.)
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Publications

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Crooke ST, Baker BF, Kwoh J, et al. (2016) Integrated Safety Assessment of 2'-O-Methoxyethyl Chimeric Antisense Oligonucleotides in Non-Human Primates and Healthy Human Volunteers. Molecular Therapy : the Journal of the American Society of Gene Therapy
Lima WF, Murray HM, Damle SS, et al. (2016) Viable RNaseH1 knockout mice show RNaseH1 is essential for R loop processing, mitochondrial and liver function. Nucleic Acids Research
Burel SA, Hart CE, Cauntay P, et al. (2015) Hepatotoxicity of high affinity gapmer antisense oligonucleotides is mediated by RNase H1 dependent promiscuous reduction of very long pre-mRNA transcripts. Nucleic Acids Research
Huang L, Damle SS, Booten S, et al. (2015) Partial Hepatectomy Induced Long Noncoding RNA Inhibits Hepatocyte Proliferation during Liver Regeneration. Plos One. 10: e0132798
Wan WB, Migawa MT, Vasquez G, et al. (2014) Synthesis, biophysical properties and biological activity of second generation antisense oligonucleotides containing chiral phosphorothioate linkages. Nucleic Acids Research. 42: 13456-68
Liang XH, Hart CE, Crooke ST. (2013) Transfection of siRNAs can alter miRNA levels and trigger non-specific protein degradation in mammalian cells. Biochimica Et Biophysica Acta. 1829: 455-68
Xu J, Yanagisawa Y, Tsankov AM, et al. (2012) Genome-wide identification and characterization of replication origins by deep sequencing. Genome Biology. 13: R27
Steinmann KE, Hart CE, Thompson JF, et al. (2011) Helicos single-molecule sequencing of bacterial genomes. Methods in Molecular Biology (Clifton, N.J.). 733: 3-24
Giladi E, Healy J, Myers G, et al. (2010) Error tolerant indexing and alignment of short reads with covering template families. Journal of Computational Biology : a Journal of Computational Molecular Cell Biology. 17: 1397-1411
Kapranov P, Ozsolak F, Kim SW, et al. (2010) New class of gene-termini-associated human RNAs suggests a novel RNA copying mechanism. Nature. 466: 642-6
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