Christopher S. Kearn, Ph.D.

Affiliations: 
Medical College of Wisconsin, Milwaukee, WI, United States 
Area:
Neuropharmacology
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"Christopher Kearn"
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Parents

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Cecilia Hillard grad student 2001 Medical College of Wisconsin
 (Cannabinoid modulation of resident immune function of the central nervous system.)
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Publications

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Morgan DJ, Davis BJ, Kearn CS, et al. (2014) Mutation of putative GRK phosphorylation sites in the cannabinoid receptor 1 (CB1R) confers resistance to cannabinoid tolerance and hypersensitivity to cannabinoids in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 5152-63
Lane DA, Chan J, Fitzgerald ML, et al. (2012) Quinpirole elicits differential in vivo changes in the pre- and postsynaptic distributions of dopamine D₂ receptors in mouse striatum: relation to cannabinoid-1 (CB₁) receptor targeting. Psychopharmacology. 221: 101-13
Chamley LW, Bhalla A, Stone PR, et al. (2008) Nuclear localisation of the endocannabinoid metabolizing enzyme fatty acid amide hydrolase (FAAH) in invasive trophoblasts and an association with recurrent miscarriage. Placenta. 29: 970-5
Malone DT, Kearn CS, Chongue L, et al. (2008) Effect of social isolation on CB1 and D2 receptor and fatty acid amide hydrolase expression in rats. Neuroscience. 152: 265-72
Daigle TL, Kearn CS, Mackie K. (2008) Rapid CB1 cannabinoid receptor desensitization defines the time course of ERK1/2 MAP kinase signaling. Neuropharmacology. 54: 36-44
Pickel VM, Chan J, Kearn CS, et al. (2006) Targeting dopamine D2 and cannabinoid-1 (CB1) receptors in rat nucleus accumbens. The Journal of Comparative Neurology. 495: 299-313
Kearn CS, Blake-Palmer K, Daniel E, et al. (2005) Concurrent stimulation of cannabinoid CB1 and dopamine D2 receptors enhances heterodimer formation: a mechanism for receptor cross-talk? Molecular Pharmacology. 67: 1697-704
Helliwell RJ, Chamley LW, Blake-Palmer K, et al. (2004) Characterization of the endocannabinoid system in early human pregnancy. The Journal of Clinical Endocrinology and Metabolism. 89: 5168-74
Carrier EJ, Kearn CS, Barkmeier AJ, et al. (2004) Cultured rat microglial cells synthesize the endocannabinoid 2-arachidonylglycerol, which increases proliferation via a CB2 receptor-dependent mechanism. Molecular Pharmacology. 65: 999-1007
Rademacher DJ, Kearn CS, Carrier EJ, et al. (2004) Production of hydroxyeicosatetraenoic acids and prostaglandins by a novel rat microglial cell line. Journal of Neuroimmunology. 149: 130-41
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