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Jamie N. Anastas, Ph.D.

Affiliations: 
Molecular and Cellular Biology University of Washington, Seattle, Seattle, WA 
Area:
Wnt signaling
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"Jamie Anastas"
Mean distance: 17.6 (cluster 11)
 		SNBCP
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Parents

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Randall Moon grad student 2012 University of Washington
 (Characterization of novel, context-dependent modulators of WNT signaling in cancer.)
Yang Shi post-doc 2013- Harvard Medical School - Boston Children's Hospital

Children

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Publications

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Zhang L, Hsu JI, Braekeleer ED, et al. (2024) is a synthetic-lethal target in -mutant leukemia cells. Elife. 12
Panditharatna E, G Marques J, Wang T, et al. (2022) BAF complex maintains glioma stem cells in pediatric H3K27M-glioma. Cancer Discovery
Jiao F, Li Z, He C, et al. (2020) RACK7 recognizes H3.3G34R mutation to suppress expression of MHC class II complex components and their delivery pathway in pediatric glioblastoma. Science Advances. 6: eaba2113
Anastas JN, Zee BM, Kalin JH, et al. (2019) Re-programing Chromatin with a Bifunctional LSD1/HDAC Inhibitor Induces Therapeutic Differentiation in DIPG. Cancer Cell
Anastas JN, Shi Y. (2019) Histone Serotonylation: Can the Brain Have "Happy" Chromatin? Molecular Cell. 74: 418-420
Jambhekar A, Anastas JN, Shi Y. (2017) Histone Lysine Demethylase Inhibitors. Cold Spring Harbor Perspectives in Medicine. 7
Anastas JN, Kulikauskas RM, Tamir T, et al. (2014) WNT5A enhances resistance of melanoma cells to targeted BRAF inhibitors. The Journal of Clinical Investigation. 124: 2877-90
Anastas JN, Moon RT. (2013) WNT signalling pathways as therapeutic targets in cancer. Nature Reviews. Cancer. 13: 11-26
Yang PT, Anastas JN, Toroni RA, et al. (2012) WLS inhibits melanoma cell proliferation through the β-catenin signalling pathway and induces spontaneous metastasis. Embo Molecular Medicine. 4: 1294-307
Anastas JN, Biechele TL, Robitaille M, et al. (2012) A protein complex of SCRIB, NOS1AP and VANGL1 regulates cell polarity and migration, and is associated with breast cancer progression. Oncogene. 31: 3696-708
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