Aaron M. Beedle, Ph.D.

Affiliations: 
University of Calgary, Calgary, Alberta, Canada 
Area:
calcium channels
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"Aaron Beedle"
Mean distance: 17.82 (cluster 11)
 
SNBCP

Parents

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Gerald W. Zamponi grad student 2003 University of Calgary
 (Cloning, characterization, and modulation of voltage -gated calcium channels.)
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Publications

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Noell S, Wolburg-Buchholz K, Mack AF, et al. (2011) Evidence for a role of dystroglycan regulating the membrane architecture of astroglial endfeet. The European Journal of Neuroscience. 33: 2179-86
Uriu Y, Kiyonaka S, Miki T, et al. (2010) Rab3-interacting molecule gamma isoforms lacking the Rab3-binding domain induce long lasting currents but block neurotransmitter vesicle anchoring in voltage-dependent P/Q-type Ca2+ channels. The Journal of Biological Chemistry. 285: 21750-67
Miki T, Kiyonaka S, Uriu Y, et al. (2007) Mutation associated with an autosomal dominant cone-rod dystrophy CORD7 modifies RIM1-mediated modulation of voltage-dependent Ca2+ channels. Channels (Austin, Tex.). 1: 144-7
Kiyonaka S, Wakamori M, Miki T, et al. (2007) RIM1 confers sustained activity and neurotransmitter vesicle anchoring to presynaptic Ca2+ channels. Nature Neuroscience. 10: 691-701
Sandoval A, Andrade A, Beedle AM, et al. (2007) Inhibition of recombinant N-type Ca(V) channels by the gamma 2 subunit involves unfolded protein response (UPR)-dependent and UPR-independent mechanisms. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 3317-27
Altier C, Khosravani H, Evans RM, et al. (2006) ORL1 receptor-mediated internalization of N-type calcium channels. Nature Neuroscience. 9: 31-40
Latour I, Louw DF, Beedle AM, et al. (2004) Expression of T-type calcium channel splice variants in human glioma. Glia. 48: 112-9
Mould J, Yasuda T, Schroeder CI, et al. (2004) The alpha2delta auxiliary subunit reduces affinity of omega-conotoxins for recombinant N-type (Cav2.2) calcium channels. The Journal of Biological Chemistry. 279: 34705-14
McRory JE, Hamid J, Doering CJ, et al. (2004) The CACNA1F gene encodes an L-type calcium channel with unique biophysical properties and tissue distribution. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 1707-18
Beedle AM, McRory JE, Poirot O, et al. (2004) Agonist-independent modulation of N-type calcium channels by ORL1 receptors. Nature Neuroscience. 7: 118-25
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