Melanie Cassella, Ph.D.

Intergrin, L1, cell migration, video microscopy, laser trap, adhesion receptors, extracellular matrix, cytoskeleton

Dan P. Felsenfeld	grad student	2008	Mount Sinai School of Medicine
(Modulation of cell migration, nuclear localization and cell cycle progression by the L1 -CAM cytoplasmic domain: Implications for tumor progression and metastasis.)

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Das S, Sarrou E, Podgrabinska S, et al. (2013) Tumor cell entry into the lymph node is controlled by CCL1 chemokine expressed by lymph node lymphatic sinuses. The Journal of Experimental Medicine. 210: 1509-28
Whittard JD, Sakurai T, Cassella MR, et al. (2006) MAP kinase pathway-dependent phosphorylation of the L1-CAM ankyrin binding site regulates neuronal growth. Molecular Biology of the Cell. 17: 2696-706
Roberts N, Kloos B, Cassella M, et al. (2006) Inhibition of VEGFR-3 activation with the antagonistic antibody more potently suppresses lymph node and distant metastases than inactivation of VEGFR-2. Cancer Research. 66: 2650-7
Gil OD, Sakurai T, Bradley AE, et al. (2003) Ankyrin binding mediates L1CAM interactions with static components of the cytoskeleton and inhibits retrograde movement of L1CAM on the cell surface. The Journal of Cell Biology. 162: 719-30