John R. Cirrito, Ph.D.

Affiliations: 
Washington University, Saint Louis, St. Louis, MO 
Area:
Alzheimer's, amyloid
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"John Cirrito"
Mean distance: 16.52 (cluster 31)
 

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David M. Holtzman grad student 2004 Washington University
 (Amyloid-beta metabolism in the brain interstitial fluid of a mouse model of Alzheimer's disease.)
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Publications

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Holth JK, Fritschi SK, Wang C, et al. (2019) The sleep-wake cycle regulates brain interstitial fluid tau in mice and CSF tau in humans. Science (New York, N.Y.)
Yuede CM, Timson BF, Hettinger JC, et al. (2018) Interactions between stress and physical activity on Alzheimer's disease pathology. Neurobiology of Stress. 8: 158-171
Hettinger JC, Lee H, Bu G, et al. (2018) AMPA-ergic regulation of amyloid-β levels in an Alzheimer's disease mouse model. Molecular Neurodegeneration. 13: 22
Liu CC, Hu J, Zhao N, et al. (2017) Astrocytic LRP1 Mediates Brain Aβ Clearance and Impacts Amyloid Deposition. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience
Fisher JR, Wallace CE, Tripoli DL, et al. (2016) Redundant Gs-coupled serotonin receptors regulate amyloid-β metabolism in vivo. Molecular Neurodegeneration. 11: 45
Hettinger JC, Cirrito JR. (2016) Bad Ac-etylated Tau. Neuron. 90: 205-6
Wang Y, Ulland TK, Ulrich JD, et al. (2016) TREM2-mediated early microglial response limits diffusion and toxicity of amyloid plaques. The Journal of Experimental Medicine
Yuede CM, Lee H, Restivo JL, et al. (2016) Rapid in vivo measurement of β-amyloid reveals biphasic clearance kinetics in an Alzheimer's mouse model. The Journal of Experimental Medicine
Liu CC, Zhao N, Yamaguchi Y, et al. (2016) Neuronal heparan sulfates promote amyloid pathology by modulating brain amyloid-β clearance and aggregation in Alzheimer's disease. Science Translational Medicine. 8: 332ra44
Moore KM, Girens RE, Larson SK, et al. (2015) A spectrum of exercise training reduces soluble Aβ in a dose-dependent manner in a mouse model of Alzheimer's disease. Neurobiology of Disease
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