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David A. DeWitt, PhD, Case Western Reserve University

Biology and Chemistry Liberty University, Lynchburg, VA, United States 
Alzheimer's disease, neurotransport
"David DeWitt"

Mean distance: 16.91 (cluster 28)
Cross-listing: Neuropathology Tree - Alzheimer's Tree - Chemistry Tree

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Shtridelman Y, Holzwarth GM, Bauer CT, et al. (2009) In vivo multimotor force-velocity curves by tracking and sizing sub-diffraction limited vesicles Cellular and Molecular Bioengineering. 2: 190-199
Dewitt DA, Hurd JA, Fox N, et al. (2006) Peri-nuclear clustering of mitochondria is triggered during aluminum maltolate induced apoptosis. Journal of Alzheimer's Disease : Jad. 9: 195-205
Griffioen KJ, Ghribi O, Fox N, et al. (2004) Aluminum maltolate-induced toxicity in NT2 cells occurs through apoptosis and includes cytochrome c release. Neurotoxicology. 25: 859-67
Ghribi O, DeWitt DA, Forbes MS, et al. (2001) Cyclosporin A inhibits Al-induced cytochrome c release from mitochondria in aged rabbits. Journal of Alzheimer's Disease : Jad. 3: 387-391
Ghribi O, Herman MM, DeWitt DA, et al. (2001) Abeta(1-42) and aluminum induce stress in the endoplasmic reticulum in rabbit hippocampus, involving nuclear translocation of gadd 153 and NF-kappaB. Brain Research. Molecular Brain Research. 96: 30-8
Ghribi O, Herman MM, Forbes MS, et al. (2001) GDNF protects against aluminum-induced apoptosis in rabbits by upregulating Bcl-2 and Bcl-XL and inhibiting mitochondrial Bax translocation. Neurobiology of Disease. 8: 764-73
Ghribi O, DeWitt DA, Forbes MS, et al. (2001) Co-involvement of mitochondria and endoplasmic reticulum in regulation of apoptosis: changes in cytochrome c, Bcl-2 and Bax in the hippocampus of aluminum-treated rabbits. Brain Research. 903: 66-73
DeWitt DA, Perry G, Cohen M, et al. (1998) Astrocytes regulate microglial phagocytosis of senile plaque cores of Alzheimer's disease. Experimental Neurology. 149: 329-40
DeWitt DA, Silver J. (1996) Regenerative failure: a potential mechanism for neuritic dystrophy in Alzheimer's disease. Experimental Neurology. 142: 103-10
Smith MA, Dewitt DA, Praprotnik D, et al. (1995) Senile plaques and neurofibrillary tangles: The concurrent lesions of alzheimer's disease Neurobiology of Aging. 16: 343-344
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