Amanda L. Woerman, Ph.D.

Affiliations: 
University of California, San Francisco, San Francisco, CA 
Area:
neurodegenerative disease, tau, synuclein, protein misfolding
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"Amanda Woerman"
Mean distance: 18.27 (cluster 22)
 

Parents

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David Mendelowitz grad student 2008-2013 The George Washington University
 (Air pollution & cardiovascular disease.)
Stanley Ben Prusiner post-doc 2013-2019 UCSF
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Publications

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Khedmatgozar CR, Holec SAM, Woerman AL. (2024) The role of α-synuclein prion strains in Parkinson's disease and multiple system atrophy. Plos Pathogens. 20: e1011920
Zeng Z, Vijayan V, Tsay K, et al. (2023) CBD and PSP cell-passaged Tau Seeds Generate Heterogeneous Fibrils with A sub-population Adopting Disease Folds. Biorxiv : the Preprint Server For Biology
Holec SAM, Lee J, Oehler A, et al. (2022) The E46K mutation modulates α-synuclein prion replication in transgenic mice. Plos Pathogens. 18: e1010956
Holec SAM, Lee J, Oehler A, et al. (2022) Multiple system atrophy prions transmit neurological disease to mice expressing wild-type human α-synuclein. Acta Neuropathologica
Holec SAM, Liu SL, Woerman AL. (2022) Consequences of variability in α-synuclein fibril structure on strain biology. Acta Neuropathologica. 143: 311-330
Ayers JI, Lee J, Monteiro O, et al. (2022) Different α-synuclein prion strains cause dementia with Lewy bodies and multiple system atrophy. Proceedings of the National Academy of Sciences of the United States of America. 119
Woerman AL, Tamgüney G. (2022) Body-first Parkinson's disease and variant Creutzfeldt-Jakob disease - similar or different? Neurobiology of Disease. 164: 105625
Lester E, Ooi FK, Bakkar N, et al. (2021) Tau aggregates are RNA-protein assemblies that mislocalize multiple nuclear speckle components. Neuron
Holec SAM, Woerman AL. (2020) Evidence of distinct α-synuclein strains underlying disease heterogeneity. Acta Neuropathologica
Woerman AL, Patel S, Kazmi SA, et al. (2020) Kinetics of α-synuclein prions preceding neuropathological inclusions in multiple system atrophy. Plos Pathogens. 16: e1008222
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