Leslie A. Crews, Ph.D.

Affiliations: 
Molecular Pathology University of California, San Diego, La Jolla, CA 
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"Leslie Crews"
Mean distance: 18.12 (cluster 32)
 
SNBCP

Parents

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Eliezer Masliah grad student 2010 UCSD
 (Molecular regulators of neurogenesis in Alzheimer's disease.)
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Publications

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Colombo M, Galletti S, Bulfamante G, et al. (2016) Multiple myeloma-derived Jagged ligands increases autocrine and paracrine interleukin-6 expression in bone marrow niche. Oncotarget
Zipeto MA, Court AC, Sadarangani A, et al. (2016) ADAR1 Activation Drives Leukemia Stem Cell Self-Renewal by Impairing Let-7 Biogenesis. Cell Stem Cell
Crews LA, Jiang Q, Zipeto MA, et al. (2015) An RNA editing fingerprint of cancer stem cell reprogramming. Journal of Translational Medicine. 13: 52
Fields JA, Dumaop W, Crews L, et al. (2015) Mechanisms of HIV-1 Tat neurotoxicity via CDK5 translocation and hyper-activation: role in HIV-associated neurocognitive disorders. Current Hiv Research. 13: 43-54
Wrasidlo W, Crews LA, Tsigelny IF, et al. (2014) Neuroprotective effects of the anti-cancer drug sunitinib in models of HIV neurotoxicity suggests potential for the treatment of neurodegenerative disorders. British Journal of Pharmacology. 171: 5757-73
Sullivan BD, Crews LA, Messmer EM, et al. (2014) Correlations between commonly used objective signs and symptoms for the diagnosis of dry eye disease: clinical implications. Acta Ophthalmologica. 92: 161-6
Jiang Q, Crews LA, Barrett CL, et al. (2013) ADAR1 promotes malignant progenitor reprogramming in chronic myeloid leukemia. Proceedings of the National Academy of Sciences of the United States of America. 110: 1041-6
Crews LA, Jamieson CH. (2013) Selective elimination of leukemia stem cells: hitting a moving target. Cancer Letters. 338: 15-22
Desplats P, Spencer B, Crews L, et al. (2012) α-Synuclein induces alterations in adult neurogenesis in Parkinson disease models via p53-mediated repression of Notch1. The Journal of Biological Chemistry. 287: 31691-702
Ma W, Gutierrez A, Goff DJ, et al. (2012) NOTCH1 signaling promotes human T-cell acute lymphoblastic leukemia initiating cell regeneration in supportive niches. Plos One. 7: e39725
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