Leslie A. Crews, Ph.D.

Affiliations: 
Molecular Pathology University of California, San Diego, La Jolla, CA 
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"Leslie Crews"
Mean distance: 18.12 (cluster 32)
 
SNBCP

Parents

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Eliezer Masliah grad student 2010 UCSD
 (Molecular regulators of neurogenesis in Alzheimer's disease.)
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Publications

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Jamieson C, Jiang Q, Holm F, et al. (2019) Inflammatory Cytokine Responsive Enzymatic Mutagenesis Fuels Myeloproliferative Neoplasm Pre-Leukemia Stem Cell Evolution Blood. 134: 3780-3780
Crews LA, Lazzari E, Mondala PK, et al. (2018) Abstract 4437: Down-modulation of ADAR1-mediated GLI1 editing alters extracellular and immune response genes in multiple myeloma Cancer Research. 78: 4437-4437
Lazzari E, Santos ND, Wu C, et al. (2017) Abstract 3351: Aberrant RNA editing of GLI1 promotes malignant regeneration in multiple myeloma Cancer Research. 77: 3351-3351
Zipeto MA, Court AC, Sadarangani A, et al. (2016) ADAR1 Activation Drives Leukemia Stem Cell Self-Renewal by Impairing Let-7 Biogenesis. Cell Stem Cell
Lazzari E, Crews LA, Wu C, et al. (2016) Abstract 2414: ADAR1-dependent RNA editing is a mechanism of therapeutic resistance in human plasma cell malignancies Cancer Research. 76: 2414-2414
Fields JA, Dumaop W, Crews L, et al. (2015) Mechanisms of HIV-1 Tat neurotoxicity via CDK5 translocation and hyper-activation: role in HIV-associated neurocognitive disorders. Current Hiv Research. 13: 43-54
Crews LA, Balaian L, Leu H, et al. (2015) RNA Splicing Modulation Impairs Acute Myeloid Leukemia Stem Cell Maintenance Blood. 126: 567-567
Lazzari E, Crews LA, Wu C, et al. (2015) Targeting Cancer Stem Cell Survival in Plasma Cell Leukemia with a Pan-BCL2 Inhibitor Blood. 126: 5351-5351
Zipeto MA, Court Recart A, Delos Santos N, et al. (2015) Inflammatory Cytokine-Responsive ADAR1 Impairs Let-7 Biogenesis and Promotes Leukemia Stem Cell Generation Blood. 126: 4014-4014
Wrasidlo W, Crews LA, Tsigelny IF, et al. (2014) Neuroprotective effects of the anti-cancer drug sunitinib in models of HIV neurotoxicity suggests potential for the treatment of neurodegenerative disorders. British Journal of Pharmacology. 171: 5757-73
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