Izumi Maezawa, Ph.D.
Affiliations: | University of Washington, Seattle, Seattle, WA |
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"Izumi Maezawa"Mean distance: 19.27 (cluster 28)
Parents
Sign in to add mentorThomas J. Montine | grad student | 2005 | University of Washington | |
(Glia-regulated, apolipoprotein E specific mechanisms of neuroprotection and neurodegeneration.) |
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Publications
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Jin LW, di Lucente J, Ruiz Mendiola U, et al. (2023) The role of FUT8-catalyzed core fucosylation in Alzheimer's amyloid-β oligomer-induced activation of human microglia. Glia |
Nguyen HM, di Lucente J, Chen YJ, et al. (2020) Biophysical basis for Kv1.3 regulation of membrane potential changes induced by P2X4-mediated calcium entry in microglia. Glia |
Jin LW, Lucente JD, Nguyen HM, et al. (2019) Repurposing the KCa3.1 inhibitor senicapoc for Alzheimer's disease. Annals of Clinical and Translational Neurology. 6: 723-738 |
Wulff H, Di Lucente J, Nguyen HM, et al. (2019) Repursposing the Kca3.1 Blocker Senicapoc as a Microglia-Targeted Therapeutic for Alzheimer's Disease Biophysical Journal. 116: 246a |
Hilt S, Altman R, Kálai T, et al. (2018) A Bifunctional Anti-Amyloid Blocks Oxidative Stress and the Accumulation of Intraneuronal Amyloid-Beta. Molecules (Basel, Switzerland). 23 |
Di Lucente J, Nguyen HM, Wulff H, et al. (2018) The voltage-gated potassium channel Kv1.3 is required for microglial pro-inflammatory activation in vivo. Glia |
Chen YJ, Nguyen HM, Maezawa I, et al. (2018) Inhibition of the potassium channel Kv1.3 reduces infarction and inflammation in ischemic stroke. Annals of Clinical and Translational Neurology. 5: 147-161 |
Jena PK, Sheng L, Di Lucente J, et al. (2018) Dysregulated bile acid synthesis and dysbiosis are implicated in Western diet-induced systemic inflammation, microglial activation, and reduced neuroplasticity. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201700984RR |
Maezawa I, Nguyen HM, Di Lucente J, et al. (2017) Kv1.3 inhibition as a potential microglia-targeted therapy for Alzheimer's disease: preclinical proof of concept. Brain : a Journal of Neurology |
Maezawa I, Zou B, Di Lucente J, et al. (2017) The Anti-Amyloid-β and Neuroprotective Properties of a Novel Tricyclic Pyrone Molecule. Journal of Alzheimer's Disease : Jad |