Brian F. Pachkowski, Ph.D.
Affiliations: | Environmental Sciences & Engineering | University of North Carolina, Chapel Hill, Chapel Hill, NC |
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Parents
Sign in to add mentor| James A. Swenberg | grad student | 2008 | UNC Chapel Hill | |
| (Functional studies of accessory factors associated with base excision repair.) | ||||
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Publications
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| Pachkowski B, Nakamura J. (2013) A neutral glyoxal gel electrophoresis method for the detection and semi-quantitation of DNA single-strand breaks. Methods in Molecular Biology (Clifton, N.J.). 1054: 133-43 |
| Pachkowski BF, Guyton KZ, Sonawane B. (2011) DNA repair during in utero development: a review of the current state of knowledge, research needs, and potential application in risk assessment. Mutation Research. 728: 35-46 |
| Luke AM, Chastain PD, Pachkowski BF, et al. (2010) Accumulation of true single strand breaks and AP sites in base excision repair deficient cells. Mutation Research. 694: 65-71 |
| Boysen G, Collins LB, Liao S, et al. (2010) Analysis of 8-oxo-7,8-dihydro-2'-deoxyguanosine by ultra high pressure liquid chromatography-heat assisted electrospray ionization-tandem mass spectrometry. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 878: 375-80 |
| Pachkowski BF, Tano K, Afonin V, et al. (2009) Cells deficient in PARP-1 show an accelerated accumulation of DNA single strand breaks, but not AP sites, over the PARP-1-proficient cells exposed to MMS. Mutation Research. 671: 93-9 |
| Boysen G, Pachkowski BF, Nakamura J, et al. (2009) The formation and biological significance of N7-guanine adducts. Mutation Research. 678: 76-94 |
| Pachkowski BF, Winkel S, Kubota Y, et al. (2006) XRCC1 genotype and breast cancer: functional studies and epidemiologic data show interactions between XRCC1 codon 280 His and smoking. Cancer Research. 66: 2860-8 |
| Rinne ML, He Y, Pachkowski BF, et al. (2005) N-methylpurine DNA glycosylase overexpression increases alkylation sensitivity by rapidly removing non-toxic 7-methylguanine adducts. Nucleic Acids Research. 33: 2859-67 |
| McDorman KS, Pachkowski BF, Nakamura J, et al. (2005) Oxidative DNA damage from potassium bromate exposure in Long-Evans rats is not enhanced by a mixture of drinking water disinfection by-products. Chemico-Biological Interactions. 152: 107-17 |
| Jeong YC, Sangaiah R, Nakamura J, et al. (2005) Analysis of M1G-dR in DNA by aldehyde reactive probe labeling and liquid chromatography tandem mass spectrometry. Chemical Research in Toxicology. 18: 51-60 |