Robert W. Walters, Ph.D.

Affiliations: 
University of Iowa, Iowa City, IA 
Area:
Cystic fibrosis, Neuroscience
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"Robert Walters"
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Robert J. Lefkowitz grad student Duke
Michael J. Welsh grad student 2003 University of Iowa
 (Viral receptor interactions in airway epithelia: Relevance to gene therapy and viral pathogenesis.)
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Publications

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Walters RW, Shukla AK, Kovacs JJ, et al. (2009) beta-Arrestin1 mediates nicotinic acid-induced flushing, but not its antilipolytic effect, in mice. The Journal of Clinical Investigation. 119: 1312-21
Walters RW, Agbandje-McKenna M, Bowman VD, et al. (2004) Structure of adeno-associated virus serotype 5. Journal of Virology. 78: 3361-71
Walters RW, Freimuth P, Moninger TO, et al. (2002) Adenovirus fiber disrupts CAR-mediated intercellular adhesion allowing virus escape. Cell. 110: 789-99
Walters RW, Pilewski JM, Chiorini JA, et al. (2002) Secreted and transmembrane mucins inhibit gene transfer with AAV4 more efficiently than AAV5. The Journal of Biological Chemistry. 277: 23709-13
Walters RW, van't Hof W, Yi SM, et al. (2001) Apical localization of the coxsackie-adenovirus receptor by glycosyl-phosphatidylinositol modification is sufficient for adenovirus-mediated gene transfer through the apical surface of human airway epithelia. Journal of Virology. 75: 7703-11
Kaludov N, Brown KE, Walters RW, et al. (2001) Adeno-associated virus serotype 4 (AAV4) and AAV5 both require sialic acid binding for hemagglutination and efficient transduction but differ in sialic acid linkage specificity. Journal of Virology. 75: 6884-93
Walters RW, Yi SM, Keshavjee S, et al. (2001) Binding of adeno-associated virus type 5 to 2,3-linked sialic acid is required for gene transfer. The Journal of Biological Chemistry. 276: 20610-6
Zabner J, Seiler M, Walters R, et al. (2000) Adeno-associated virus type 5 (AAV5) but not AAV2 binds to the apical surfaces of airway epithelia and facilitates gene transfer. Journal of Virology. 74: 3852-8
Walters RW, Duan D, Engelhardt JF, et al. (2000) Incorporation of adeno-associated virus in a calcium phosphate coprecipitate improves gene transfer to airway epithelia in vitro and in vivo. Journal of Virology. 74: 535-40
Walters RW, Welsh MJ. (1999) Mechanism by which calcium phosphate coprecipitation enhances adenovirus-mediated gene transfer Gene Therapy. 6: 1845-1850
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