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Shusei Hamamichi, Ph.D.

Affiliations: 
2009 Biological Sciences The University of Alabama, Tuscaloosa, AL 
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"Shusei Hamamichi"
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Parents

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Guy Caldwell grad student 2009 University of Alabama
 (Identification of neuroprotective genes against alpha-synuclein toxicity using a Caenorhabditis elegans Parkinson disease model.)

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Publications

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Gaeta AL, Nourse JB, Willicott K, et al. (2022) Systemic RNA Interference Defective (SID) genes modulate dopaminergic neurodegeneration in C. elegans. Plos Genetics. 18: e1010115
Knight AL, Yan X, Hamamichi S, et al. (2014) The glycolytic enzyme, GPI, is a functionally conserved modifier of dopaminergic neurodegeneration in Parkinson's models. Cell Metabolism. 20: 145-57
Matlack KE, Tardiff DF, Narayan P, et al. (2014) Clioquinol promotes the degradation of metal-dependent amyloid-β (Aβ) oligomers to restore endocytosis and ameliorate Aβ toxicity. Proceedings of the National Academy of Sciences of the United States of America. 111: 4013-8
Muñoz-Lobato F, Rodríguez-Palero MJ, Naranjo-Galindo FJ, et al. (2014) Protective role of DNJ-27/ERdj5 in Caenorhabditis elegans models of human neurodegenerative diseases. Antioxidants & Redox Signaling. 20: 217-35
Treusch S, Hamamichi S, Goodman JL, et al. (2011) Functional links between Aβ toxicity, endocytic trafficking, and Alzheimer's disease risk factors in yeast. Science (New York, N.Y.). 334: 1241-5
Liu Z, Hamamichi S, Lee BD, et al. (2011) Inhibitors of LRRK2 kinase attenuate neurodegeneration and Parkinson-like phenotypes in Caenorhabditis elegans and Drosophila Parkinson's disease models. Human Molecular Genetics. 20: 3933-42
Yacoubian TA, Slone SR, Harrington AJ, et al. (2010) Differential neuroprotective effects of 14-3-3 proteins in models of Parkinson's disease. Cell Death & Disease. 1: e2
Harrington AJ, Hamamichi S, Caldwell GA, et al. (2010) C. elegans as a model organism to investigate molecular pathways involved with Parkinson's disease. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 239: 1282-95
Su LJ, Auluck PK, Outeiro TF, et al. (2010) Compounds from an unbiased chemical screen reverse both ER-to-Golgi trafficking defects and mitochondrial dysfunction in Parkinson's disease models. Disease Models & Mechanisms. 3: 194-208
Kritzer JA, Hamamichi S, McCaffery JM, et al. (2009) Rapid selection of cyclic peptides that reduce alpha-synuclein toxicity in yeast and animal models. Nature Chemical Biology. 5: 655-63
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