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Michael P. Hart

Affiliations: 
University of Vermont, Burlington, VT, United States 
Area:
Neurodegeneration
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"Michael Hart"
Mean distance: 17.79 (cluster 32)
 		SNBCP
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Parents

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Joseph Erlichman research assistant 2003-2006 St. Lawrence University
Felix Eckenstein research assistant 2006-2008 University of Vermont
Rae Nishi research assistant 2007-2008 University of Vermont
Aaron D. Gitler grad student 2012 Penn
 (Defining the mechanisms of ataxin 2 polyglutamine expansions in Amyotrophic Lateral Sclerosis.)

Children

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Collaborators

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John C. DeWitt collaborator 2007-2007 UVM
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Publications

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Hart MP. (2019) Stress-Induced Neuron Remodeling Reveals Differential Interplay Between Neurexin and Environmental Factors in . Genetics
Hart MP, Hobert O. (2018) Neurexin controls plasticity of a mature, sexually dimorphic neuron. Nature. 553: 165-170
Kerk SY, Kratsios P, Hart M, et al. (2017) Diversification of C. elegans Motor Neuron Identity via Selective Effector Gene Repression. Neuron. 93: 80-98
Coyne AN, Yamada SB, Siddegowda BB, et al. (2015) Fragile X protein mitigates TDP-43 toxicity by remodeling RNA granules and restoring translation. Human Molecular Genetics
Hart MP, Gitler AD. (2012) ALS-associated ataxin 2 polyQ expansions enhance stress-induced caspase 3 activation and increase TDP-43 pathological modifications. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 9133-42
Hart MP, Brettschneider J, Lee VM, et al. (2012) Distinct TDP-43 pathology in ALS patients with ataxin 2 intermediate-length polyQ expansions. Acta Neuropathologica. 124: 221-30
Couthouis J, Hart MP, Erion R, et al. (2012) Evaluating the role of the FUS/TLS-related gene EWSR1 in amyotrophic lateral sclerosis. Human Molecular Genetics. 21: 2899-911
Couthouis J, Hart MP, Shorter J, et al. (2011) A yeast functional screen predicts new candidate ALS disease genes. Proceedings of the National Academy of Sciences of the United States of America. 108: 20881-90
Lee T, Li YR, Chesi A, et al. (2011) Evaluating the prevalence of polyglutamine repeat expansions in amyotrophic lateral sclerosis. Neurology. 76: 2062-5
Sun Z, Diaz Z, Fang X, et al. (2011) Molecular determinants and genetic modifiers of aggregation and toxicity for the ALS disease protein FUS/TLS. Plos Biology. 9: e1000614
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