Robert S. Freeman
Affiliations: | University of Rochester, Rochester, NY |
Area:
Developmental Cell Ceath in the Nervous SystemGoogle:
"Robert Freeman"Mean distance: 16.15 (cluster 11) | S | N | B | C | P |
Parents
Sign in to add mentorDaniel J. Donoghue | grad student | 1988-1992 | UCSD (Chemistry Tree) |
Eugene M. Johnson | post-doc | Washington University School of Medicine |
Children
Sign in to add traineeElizabeth A. Lipscomb | grad student | 2001 | Rochester |
Patrick D. Sarmiere | grad student | 2002 | Rochester |
Jennifer A. Straub | grad student | 2000-2004 | Rochester |
David J. Lomb | grad student | 2007 | Rochester |
Yanan Guo | grad student | 2008 | Rochester |
Carolyn M. Tyler | grad student | 2006-2009 | Rochester |
Lynette A. Desouza | grad student | 2010 | Rochester |
Kathleen M. McAvoy | grad student | 2011 | Rochester |
Makaía M. Papasergi-Scott | grad student | 2016-2017 | University of Rochester Medical Center (Chemistry Tree) |
Collaborators
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Publications
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Papasergi-Scott MM, Stoveken HM, MacConnachie L, et al. (2018) Dual phosphorylation of Ric-8A enhances its ability to mediate G protein α subunit folding and to stimulate guanine nucleotide exchange. Science Signaling. 11 |
Guo H, Barrett TM, Zhong Z, et al. (2011) Protein S blocks the extrinsic apoptotic cascade in tissue plasminogen activator/N-methyl D-aspartate-treated neurons via Tyro3-Akt-FKHRL1 signaling pathway. Molecular Neurodegeneration. 6: 13 |
Zhong Z, Wang Y, Guo H, et al. (2010) Protein S protects neurons from excitotoxic injury by activating the TAM receptor Tyro3-phosphatidylinositol 3-kinase-Akt pathway through its sex hormone-binding globulin-like region. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 15521-34 |
Guo Y, Schoell MC, Freeman RS. (2009) The von Hippel-Lindau protein sensitizes renal carcinoma cells to apoptotic stimuli through stabilization of BIM(EL). Oncogene. 28: 1864-74 |
Lomb DJ, Desouza LA, Franklin JL, et al. (2009) Prolyl hydroxylase inhibitors depend on extracellular glucose and hypoxia-inducible factor (HIF)-2alpha to inhibit cell death caused by nerve growth factor (NGF) deprivation: evidence that HIF-2alpha has a role in NGF-promoted survival of sympathetic neurons. Molecular Pharmacology. 75: 1198-209 |
Ratan RR, Siddiq A, Aminova L, et al. (2008) Small molecule activation of adaptive gene expression: tilorone or its analogs are novel potent activators of hypoxia inducible factor-1 that provide prophylaxis against stroke and spinal cord injury. Annals of the New York Academy of Sciences. 1147: 383-94 |
Barone MC, Desouza LA, Freeman RS. (2008) Pin1 promotes cell death in NGF-dependent neurons through a mechanism requiring c-Jun activity. Journal of Neurochemistry. 106: 734-45 |
Lomb DJ, Straub JA, Freeman RS. (2007) Prolyl hydroxylase inhibitors delay neuronal cell death caused by trophic factor deprivation. Journal of Neurochemistry. 103: 1897-906 |
Fu J, Menzies K, Freeman RS, et al. (2007) EGLN3 prolyl hydroxylase regulates skeletal muscle differentiation and myogenin protein stability. The Journal of Biological Chemistry. 282: 12410-8 |
Lee S, Nakamura E, Yang H, et al. (2005) Neuronal apoptosis linked to EglN3 prolyl hydroxylase and familial pheochromocytoma genes: developmental culling and cancer. Cancer Cell. 8: 155-67 |