Avak Kahvejian, Ph.D.
Affiliations: | 2004 | McGill University, Montreal, QC, Canada |
Area:
translational controlGoogle:
"Avak Kahvejian"Mean distance: 17.39 (cluster 6) | S | N | B | C | P |
Parents
Sign in to add mentor| Nahum Sonenberg | grad student | 2004 | McGill | |
| (Characterization of the poly(A) binding protein and its interacting partners: Understanding the poly(A) tail's role in mRNA translation.) | ||||
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Publications
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| Khanam T, Muddashetty RS, Kahvejian A, et al. (2006) Poly(A)-binding protein binds to A-rich sequences via RNA-binding domains 1+2 and 3+4. Rna Biology. 3: 170-7 |
| Karim MM, Svitkin YV, Kahvejian A, et al. (2006) A mechanism of translational repression by competition of Paip2 with eIF4G for poly(A) binding protein (PABP) binding. Proceedings of the National Academy of Sciences of the United States of America. 103: 9494-9 |
| Yoshida M, Yoshida K, Kozlov G, et al. (2006) Poly(A) binding protein (PABP) homeostasis is mediated by the stability of its inhibitor, Paip2. The Embo Journal. 25: 1934-44 |
| Kahvejian A, Svitkin YV, Sukarieh R, et al. (2005) Mammalian poly(A)-binding protein is a eukaryotic translation initiation factor, which acts via multiple mechanisms. Genes & Development. 19: 104-13 |
| Chang TC, Yamashita A, Chen CY, et al. (2004) UNR, a new partner of poly(A)-binding protein, plays a key role in translationally coupled mRNA turnover mediated by the c-fos major coding-region determinant. Genes & Development. 18: 2010-23 |
| Kozlov G, De Crescenzo G, Lim NS, et al. (2004) Structural basis of ligand recognition by PABC, a highly specific peptide-binding domain found in poly(A)-binding protein and a HECT ubiquitin ligase. The Embo Journal. 23: 272-81 |
| Roy G, De Crescenzo G, Khaleghpour K, et al. (2002) Paip1 interacts with poly(A) binding protein through two independent binding motifs. Molecular and Cellular Biology. 22: 3769-82 |
| Kahvejian A, Roy G, Sonenberg N. (2001) The mRNA closed-loop model: the function of PABP and PABP-interacting proteins in mRNA translation. Cold Spring Harbor Symposia On Quantitative Biology. 66: 293-300 |
| Svitkin YV, Imataka H, Khaleghpour K, et al. (2001) Poly(A)-binding protein interaction with elF4G stimulates picornavirus IRES-dependent translation. Rna (New York, N.Y.). 7: 1743-52 |
| Khaleghpour K, Kahvejian A, De Crescenzo G, et al. (2001) Dual interactions of the translational repressor Paip2 with poly(A) binding protein. Molecular and Cellular Biology. 21: 5200-13 |