Margaret G. Distler, Ph.D.

Affiliations: 
2012 Pathology University of Chicago, Chicago, IL 
Area:
behavioral genetics
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"Margaret Distler"
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SNBCP

Parents

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Abraham Palmer grad student 2012 Chicago
 (The glyoxalase system regulates GABAA receptors and downstream behaviors.)

Children

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Andrew Swenson research assistant 2021-
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Publications

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Spivak NM, Haroon J, Swenson A, et al. (2022) Microbiome in Anxiety and Other Psychiatric Disorders. The Medical Clinics of North America. 107: 73-83
Bystritsky A, Spivak NM, Dang BH, et al. (2021) Brain circuitry underlying the ABC model of anxiety. Journal of Psychiatric Research. 138: 3-14
Gonzales NM, Seo J, Hernandez Cordero AI, et al. (2018) Genome wide association analysis in a mouse advanced intercross line. Nature Communications. 9: 5162
McMurray KM, Distler MG, Sidhu PS, et al. (2014) Glo1 inhibitors for neuropsychiatric and anti-epileptic drug development. Biochemical Society Transactions. 42: 461-7
Distler MG, Gorfinkle N, Papale LA, et al. (2013) Glyoxalase 1 and its substrate methylglyoxal are novel regulators of seizure susceptibility. Epilepsia. 54: 649-57
Distler MG, Opal MD, Dulawa SC, et al. (2012) Assessment of behaviors modeling aspects of schizophrenia in Csmd1 mutant mice. Plos One. 7: e51235
Distler MG, Palmer AA. (2012) Role of Glyoxalase 1 (Glo1) and methylglyoxal (MG) in behavior: recent advances and mechanistic insights. Frontiers in Genetics. 3: 250
Distler MG, Plant LD, Sokoloff G, et al. (2012) Glyoxalase 1 increases anxiety by reducing GABAA receptor agonist methylglyoxal. The Journal of Clinical Investigation. 122: 2306-15
Savic D, Distler MG, Sokoloff G, et al. (2011) Modulation ofTcf7l2 expression alters behavior in mice. Plos One. 6: e26897
Williams R, Lim JE, Harr B, et al. (2009) A common and unstable copy number variant is associated with differences in Glo1 expression and anxiety-like behavior. Plos One. 4: e4649
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