Xianyuan Xiang

2013- BMC Ludwig Maximilian University, München, Bayern, Germany 
Neurodegenerative disease
"Xianyuan Xiang"
Mean distance: 19.66 (cluster 31)
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Gnörich J, Reifschneider A, Wind K, et al. (2023) Depletion and activation of microglia impact metabolic connectivity of the mouse brain. Journal of Neuroinflammation. 20: 47
Xiang X, Tahirovic S, Ziegler S, et al. (2022) Response to Comment on "Microglial activation states drive glucose uptake and FDG-PET alterations in neurodegenerative diseases". Science Translational Medicine. 14: eabn5104
Bartos LM, Kunte ST, Beumers P, et al. (2022) Single cell radiotracer allocation via immunomagentic sorting (scRadiotracing) to disentangle PET signals at cellular resolution. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine
Xiang X, Wind K, Wiedemann T, et al. (2021) Microglial activation states drive glucose uptake and FDG-PET alterations in neurodegenerative diseases. Science Translational Medicine. 13: eabe5640
Takalo M, Wittrahm R, Wefers B, et al. (2020) The Alzheimer's disease-associated protective Plcγ2-P522R variant promotes immune functions. Molecular Neurodegeneration. 15: 52
Schlepckow K, Monroe KM, Kleinberger G, et al. (2020) Enhancing protective microglial activities with a dual function TREM2 antibody to the stalk region. Embo Molecular Medicine. e11227
Xiang X, Piers TM, Wefers B, et al. (2018) The Trem2 R47H Alzheimer's risk variant impairs splicing and reduces Trem2 mRNA and protein in mice but not in humans. Molecular Neurodegeneration. 13: 49
Kleinberger G, Brendel M, Mracsko E, et al. (2017) The FTD-like syndrome causing TREM2 T66M mutation impairs microglia function, brain perfusion, and glucose metabolism. The Embo Journal
Zhu K, Xiang X, Filser S, et al. (2016) Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 Inhibition Impairs Synaptic Plasticity via Seizure Protein 6. Biological Psychiatry
Xiang X, Werner G, Bohrmann B, et al. (2016) TREM2 deficiency reduces the efficacy of immunotherapeutic amyloid clearance. Embo Molecular Medicine
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