Vivek Kumar, Ph.D

2015- The Jackson Laboratory, Bar Harbor, ME, United States 
Addiction, Forward Genetics, Mouse Genetics
"vivek kumar jackson laboratory"

The Kumar lab studies neural circuits in the brain whose misregulation leads to behavioral abnormalities including addiction, attention deficit and hyperactivity disorder,and depression. Using mouse molecular genetics as a foundation, and a combination of biochemistry, physiology, and imaging techniques, we dissect these complex behaviors in mammals.

Mean distance: 16.24 (cluster 31)


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Robert Haselkorn research assistant Chicago (Chemistry Tree)
Michael G. Rosenfeld grad student 1998-2003 UCSD
 (Characterization of the transcription corepressor C -terminal binding protein (CtBP).)
Joseph S. Takahashi post-doc 2004-
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Takahashi JS, Kumar V, Nakashe P, et al. (2015) ChIP-seq and RNA-seq methods to study circadian control of transcription in mammals. Methods in Enzymology. 551: 285-321
Plikus MV, Van Spyk EN, Pham K, et al. (2015) The circadian clock in skin: implications for adult stem cells, tissue regeneration, cancer, aging, and immunity. Journal of Biological Rhythms. 30: 163-82
Stringari C, Wang H, Geyfman M, et al. (2015) In vivo single-cell detection of metabolic oscillations in stem cells. Cell Reports. 10: 1-7
Kim TJ, Kim M, Kim HM, et al. (2014) Homotypic NK cell-to-cell communication controls cytokine responsiveness of innate immune NK cells. Scientific Reports. 4: 7157
Kumar V, Kim K, Joseph C, et al. (2013) C57BL/6N mutation in cytoplasmic FMRP interacting protein 2 regulates cocaine response. Science (New York, N.Y.). 342: 1508-12
Kumar V, Andersen B, Takahashi JS. (2013) Epidermal stem cells ride the circadian wave. Genome Biology. 14: 140
Shimomura K, Kumar V, Koike N, et al. (2013) Usf1, a suppressor of the circadian Clock mutant, reveals the nature of the DNA-binding of the CLOCK:BMAL1 complex in mice. Elife. 2: e00426
Yoo SH, Mohawk JA, Siepka SM, et al. (2013) Competing E3 ubiquitin ligases govern circadian periodicity by degradation of CRY in nucleus and cytoplasm. Cell. 152: 1091-105
Koike N, Yoo SH, Huang HC, et al. (2012) Transcriptional architecture and chromatin landscape of the core circadian clock in mammals. Science (New York, N.Y.). 338: 349-54
Geyfman M, Kumar V, Liu Q, et al. (2012) Brain and muscle Arnt-like protein-1 (BMAL1) controls circadian cell proliferation and susceptibility to UVB-induced DNA damage in the epidermis. Proceedings of the National Academy of Sciences of the United States of America. 109: 11758-63
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