Joost Smolders, M.D./Ph.D.

Affiliations: 
2007-2011 Experimental Immunology. Academic MS Center Maastricht University Medical Center+ 
 2011-2012 Neuroimmunology Netherlands Institute for Neuroscience, Amsterdam, NL 
 2012-2013 Neurology St Antonius Ziekenhuis 
 2013-2014 Neurology Radboud University Medical Center 
 2014- Neurology Canisius Wilhelmina Ziekenhuis 
Area:
Multiple Sclerosis, neuroscience, immunology, vitamin D
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Raymond Hupperts grad student 2007-2011 Maastricht University Medical Center+
 (Thesis "vitamin D as an immune modulator in multiple sclerosis")
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Publications

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van den Bosch AMR, van der Poel M, Fransen NL, et al. (2024) Profiling of microglia nodules in multiple sclerosis reveals propensity for lesion formation. Nature Communications. 15: 1667
Blok KM, van Rosmalen J, Tebayna N, et al. (2023) Disease activity in primary progressive multiple sclerosis: a systematic review and meta-analysis. Frontiers in Neurology. 14: 1277477
Hoeks C, Puijfelik FV, Koetzier SC, et al. (2023) Differential Runx3, Eomes, and T-bet expression subdivides MS-associated CD4 T cells with brain-homing capacity. European Journal of Immunology. e2350544
Bogers L, Engelenburg HJ, Janssen M, et al. (2023) Selective emergence of antibody-secreting cells in the multiple sclerosis brain. Ebiomedicine. 89: 104465
Rijvers L, van Langelaar J, Bogers L, et al. (2022) Human T-bet+ B cell development is associated with BTK activity and suppressed by evobrutinib. Jci Insight. 7
Koetzier SC, van Langelaar J, Wierenga-Wolf AF, et al. (2022) Improving Glucocorticoid Sensitivity of Brain-Homing CD4 T Helper Cells by Steroid Hormone Crosstalk. Frontiers in Immunology. 13: 893702
Mimpen M, Rolf L, Poelmans G, et al. (2021) Vitamin D related genetic polymorphisms affect serological response to high-dose vitamin D supplementation in multiple sclerosis. Plos One. 16: e0261097
Mimpen M, Damoiseaux J, van Doorn W, et al. (2021) Proportions of circulating transitional B cells associate with MRI activity in interferon beta-treated multiple sclerosis patients. Journal of Neuroimmunology. 358: 577664
Koetzier SC, Neuteboom RF, Wierenga-Wolf AF, et al. (2021) Effector T Helper Cells Are Selectively Controlled During Pregnancy and Related to a Postpartum Relapse in Multiple Sclerosis. Frontiers in Immunology. 12: 642038
Smolders J, Hiller A, Camu W. (2021) Editorial: Vitamin D in Neurological Diseases: From Pathophysiology to Therapy. Frontiers in Neurology. 12: 614900
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