Bruce A Edgar

Affiliations: 
1993-2009 Fred Hutchinson Cancer Research Center, Seattle, WA, United States 
 2009-2016 Ruprecht-Karls-Universität Heidelberg, Heidelberg, Baden-Württemberg, Germany 
 2016- Huntsman Cancer Institute University of Utah, Salt Lake City, UT 
Area:
cell growth and proliferation in the fruit fly, Drosophila melanogaster
Website:
https://medicine.utah.edu/faculty/mddetail.php?facultyID=u6000141
Google:
"Bruce Alexander Edgar" OR "Bruce A Edgar"

Parents

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Gerold Schubiger grad student 1987 University of Washington
 (Early events in Drosophila development)
Pat H. O'Farrell post-doc UCSF
Paul Nurse post-doc 1993 Oxford (PombeTree)

Collaborators

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Stephen Cohen collaborator
BETA: Related publications

Publications

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Øvrebø JI, Ma Y, Edgar BA. (2022) Cell growth and the cell cycle: New insights about persistent questions. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 44: e2200150
Zhang C, Jin Y, Marchetti M, et al. (2022) EGFR signaling activates intestinal stem cells by promoting mitochondrial biogenesis and β-oxidation. Current Biology : Cb
Øvrebø JI, Bradley-Gill MR, Zielke N, et al. (2022) Translational control of regulates the cell cycle. Proceedings of the National Academy of Sciences of the United States of America. 119
Zhang P, Edgar BA. (2021) Insect Gut Regeneration. Cold Spring Harbor Perspectives in Biology
Ma Y, Edgar BA. (2021) CDK4: Linking cell size to cell cycle control. Developmental Cell. 56: 1695-1696
Tauc HM, Rodriguez-Fernandez IA, Hackney JA, et al. (2021) Age-related changes in Polycomb gene regulation disrupt lineage fidelity in intestinal stem cells. Elife. 10
Zhang P, Katzaroff AJ, Buttitta LA, et al. (2021) The Krüppel-like factor Cabut has cell cycle regulatory properties similar to E2F1. Proceedings of the National Academy of Sciences of the United States of America. 118
Zhang P, Edgar BA. (2020) Lipoic acid and autophagy: new insights into stem cell aging. Embo Reports. e202051175
Ahmed SMH, Maldera JA, Krunic D, et al. (2020) Fitness trade-offs incurred by ovary-to-gut steroid signalling in Drosophila. Nature
Zhang P, Pei C, Yuan Z, et al. (2020) Abstract A15: A balance of yki/sd activator and e2f1/sd repressor complexes controls cell survival and affects organ size Molecular Cancer Research. 18
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