Amit U. Sinha, Ph.D.
Affiliations: | 2008 | University of Cincinnati, Cincinnati, OH |
Area:
bioinformatics, computational genomics, protein structureGoogle:
"Amit Sinha"Mean distance: 28.34 | S | N | B | C | P |
Parents
Sign in to add mentor| Jaroslaw Meller | grad student | 2008 | University of Cincinnati | |
| (Discovery and analysis of genomic patterns: Applications to transcription factor binding and genome rearrangement.) | ||||
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Publications
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| Bamezai S, Demir D, Pulikkottil AJ, et al. (2020) TET1 promotes growth of T-cell acute lymphoblastic leukemia and can be antagonized via PARP inhibition. Leukemia |
| Micol JB, Pastore A, Inoue D, et al. (2017) ASXL2 is essential for haematopoiesis and acts as a haploinsufficient tumour suppressor in leukemia. Nature Communications. 8: 15429 |
| Gala K, Sinha A, Sanchez-Vega F, et al. (2017) Abstract 5500: KMT2C directs estrogen receptor activity in normal and transformed mammary cells Cancer Research. 77: 5500-5500 |
| Xu H, Valerio DG, Eisold ME, et al. (2016) NUP98 Fusion Proteins Interact with the NSL and MLL1 Complexes to Drive Leukemogenesis. Cancer Cell |
| Kühn MW, Song E, Feng Z, et al. (2016) Targeting Chromatin Regulators Inhibits Leukemogenic Gene Expression in NPM1 Mutant Leukemia. Cancer Discovery |
| Riedel SS, Haladyna JN, Bezzant M, et al. (2016) MLL1 and DOT1L cooperate with meningioma-1 to induce acute myeloid leukemia. The Journal of Clinical Investigation |
| Zhu N, Chen M, Eng R, et al. (2016) MLL-AF9- and HOXA9-mediated acute myeloid leukemia stem cell self-renewal requires JMJD1C. The Journal of Clinical Investigation |
| Chen CW, Koche RP, Sinha AU, et al. (2015) DOT1L inhibits SIRT1-mediated epigenetic silencing to maintain leukemic gene expression in MLL-rearranged leukemia. Nature Medicine. 21: 335-43 |
| Deshpande AJ, Deshpande A, Sinha AU, et al. (2014) AF10 regulates progressive H3K79 methylation and HOX gene expression in diverse AML subtypes. Cancer Cell. 26: 896-908 |
| Ng CE, Sinha A, Krivtsov A, et al. (2014) KRas(G12D)-evoked leukemogenesis does not require β-catenin. Leukemia. 28: 698-702 |