Tatsuya Maehigashi, Ph.D.

2009 Georgia Institute of Technology, Atlanta, GA 
DNA, intercalators, crystallography, RNA, ribosome, evolution
"Tatsuya Maehigashi"
Mean distance: 18.06


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Loren Dean Williams grad student 2009 Georgia Tech
 (Ultra-high resolution DNA crystallography.)
Christine M. Dunham post-doc Emory (Chemistry Tree)
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Hoffer E, Hong S, Sunita S, et al. (2020) Structural insights into mRNA reading frame regulation by tRNA modification and slippery codon-anticodon pairing. Elife. 9
Pavelich IJ, Maehigashi T, Hoffer ED, et al. (2019) Monomeric YoeB toxin retains RNase activity but adopts an obligate dimeric form for thermal stability. Nucleic Acids Research
Hoffer ED, Maehigashi T, Fredrick K, et al. (2018) Ribosomal ambiguity (ram) mutations promote the open (off) to closed (on) transition and thereby increase miscoding. Nucleic Acids Research
Hong S, Sunita S, Maehigashi T, et al. (2018) Mechanism of tRNA-mediated +1 ribosomal frameshifting. Proceedings of the National Academy of Sciences of the United States of America
Ruangprasert A, Maehigashi T, Miles SJ, et al. (2017) Importance of the E. coli DinJ antitoxin carboxy terminus for toxin suppression and regulated proteolysis. Molecular Microbiology
Schureck MA, Maehigashi T, Miles SJ, et al. (2016) mRNA bound to the 30S subunit is a HigB toxin substrate. Rna (New York, N.Y.)
Schureck MA, Dunkle JA, Maehigashi T, et al. (2015) Defining the mRNA recognition signature of a bacterial toxin protein. Proceedings of the National Academy of Sciences of the United States of America. 112: 13862-7
Maehigashi T, Ruangprasert A, Miles SJ, et al. (2015) Molecular basis of ribosome recognition and mRNA hydrolysis by the E. coli YafQ toxin. Nucleic Acids Research. 43: 8002-12
Cruz JW, Sharp JD, Hoffer ED, et al. (2015) Growth-regulating Mycobacterium tuberculosis VapC-mt4 toxin is an isoacceptor-specific tRNase. Nature Communications. 6: 7480
Fagan CE, Maehigashi T, Dunkle JA, et al. (2014) Structural insights into translational recoding by frameshift suppressor tRNASufJ. Rna (New York, N.Y.). 20: 1944-54
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