Tatsuya Maehigashi, Ph.D.

Affiliations: 
2009 Georgia Institute of Technology, Atlanta, GA 
Area:
DNA, intercalators, crystallography, RNA, ribosome, evolution
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"Tatsuya Maehigashi"
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Parents

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Loren Dean Williams grad student 2009 Georgia Tech
 (Ultra-high resolution DNA crystallography.)
Christine M. Dunham post-doc Emory (Chemistry Tree)
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Publications

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Nguyen HA, Hoffer ED, Fagan CE, et al. (2023) Structural basis for reduced ribosomal A-site fidelity in response to P-site codon-anticodon mismatches. The Journal of Biological Chemistry. 299: 104608
Nguyen HA, Hoffer ED, Fagan CE, et al. (2023) Structural basis for reduced ribosomal A-site fidelity in response to P-site codon-anticodon mismatches. Biorxiv : the Preprint Server For Biology
Hoffer E, Hong S, Sunita S, et al. (2020) Structural insights into mRNA reading frame regulation by tRNA modification and slippery codon-anticodon pairing. Elife. 9
Dunham C, Hoffer ED, An Nguyen H, et al. (2020) Role of RNA Modifications in tRNA Structural Stability and Accurate Protein Synthesis Biophysical Journal. 118: 181a-182a
Harris DC, Garcia YA, Samaniego CS, et al. (2019) Functional Comparison of Human and Zebra Fish FKBP52 Confirms the Importance of the Proline-Rich Loop for Regulation of Steroid Hormone Receptor Activity. International Journal of Molecular Sciences. 20
Pavelich IJ, Maehigashi T, Hoffer ED, et al. (2019) Monomeric YoeB toxin retains RNase activity but adopts an obligate dimeric form for thermal stability. Nucleic Acids Research
Hoffer ED, Maehigashi T, Fredrick K, et al. (2018) Ribosomal ambiguity (ram) mutations promote the open (off) to closed (on) transition and thereby increase miscoding. Nucleic Acids Research
Hong S, Sunita S, Maehigashi T, et al. (2018) Mechanism of tRNA-mediated +1 ribosomal frameshifting. Proceedings of the National Academy of Sciences of the United States of America
Ruangprasert A, Maehigashi T, Miles SJ, et al. (2017) Importance of the E. coli DinJ antitoxin carboxy terminus for toxin suppression and regulated proteolysis. Molecular Microbiology
Hong S, Sunita S, Schureck MA, et al. (2017) Molecular mechanisms of translational control Acta Crystallographica Section a Foundations and Advances. 73: a431-a431
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