Ian J. Orozco, Ph.D.

Affiliations: 
2011 Cellular, Molecular and Biomedical Studies Columbia University, New York, NY 
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Ottavio Arancio grad student 2011 Columbia
 (Functional Characterization of Hippocampal Synapses in a Mouse Model Containing a Mutation in the Dystrobrevin Binding Protein 1 (DTNBP 1) Gene.)
Juan Du research scientist 2022 Van Andel Institute (Chemistry Tree)
Wei Lü research scientist 2022 Van Andel Institute (Chemistry Tree)
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Publications

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Ruan Z, Haley E, Orozco IJ, et al. (2021) Author Correction: Structures of the TRPM5 channel elucidate mechanisms of activation and inhibition. Nature Structural & Molecular Biology
Ruan Z, Haley E, Orozco IJ, et al. (2021) Structures of the TRPM5 channel elucidate mechanisms of activation and inhibition. Nature Structural & Molecular Biology
Ruan Z, Orozco IJ, Du J, et al. (2020) Structures of human pannexin 1 reveal ion pathways and mechanism of gating. Nature
Koppensteiner P, Trinchese F, Fà M, et al. (2016) Time-dependent reversal of synaptic plasticity induced by physiological concentrations of oligomeric Aβ42: an early index of Alzheimer's disease. Scientific Reports. 6: 32553
Lee L, Dale E, Staniszewski A, et al. (2015) Corrigendum: Regulation of synaptic plasticity and cognition by SUMO in normal physiology and Alzheimer's disease. Scientific Reports. 5: 11782
Lee L, Dale E, Staniszewski A, et al. (2014) Regulation of synaptic plasticity and cognition by SUMO in normal physiology and Alzheimer's disease. Scientific Reports. 4: 7190
Orozco IJ, Koppensteiner P, Ninan I, et al. (2014) The schizophrenia susceptibility gene DTNBP1 modulates AMPAR synaptic transmission and plasticity in the hippocampus of juvenile DBA/2J mice. Molecular and Cellular Neurosciences. 58: 76-84
Ren H, Orozco I, Su Y, et al. (2013) FoxO1 Target Gpr17 Activates AgRP Neurons to Regulate Food Intake Cell. 153: 1166
Ren H, Orozco IJ, Su Y, et al. (2012) FoxO1 target Gpr17 activates AgRP neurons to regulate food intake. Cell. 149: 1314-26
Fa M, Orozco IJ, Francis YI, et al. (2010) Preparation of oligomeric beta-amyloid 1-42 and induction of synaptic plasticity impairment on hippocampal slices. Journal of Visualized Experiments : Jove
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