Frankis G. Almaguel, Ph.D.

Affiliations: 
2010 Loma Linda University, Loma Linda, United States 
Area:
Nerve regeneration, neuronal injury, neuropathic pain, health disparities, STEM
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"Frankis Almaguel"
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Marino De Leon grad student 2010 Loma Linda University
 (Mechanisms of DHA neuroprotection from PA induced lipotoxicity.)
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Publications

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Pacheco FJ, Almaguel FG, Evans W, et al. (2014) Docosahexanoic acid antagonizes TNF-α-induced necroptosis by attenuating oxidative stress, ceramide production, lysosomal dysfunction, and autophagic features. Inflammation Research : Official Journal of the European Histamine Research Society ... [Et Al.]. 63: 859-71
Figueroa JD, Cordero K, Serrano-Illan M, et al. (2013) Metabolomics uncovers dietary omega-3 fatty acid-derived metabolites implicated in anti-nociceptive responses after experimental spinal cord injury. Neuroscience. 255: 1-18
Almaguel FG, Liu JW, Pacheco FJ, et al. (2010) Lipotoxicity-mediated cell dysfunction and death involve lysosomal membrane permeabilization and cathepsin L activity. Brain Research. 1318: 133-43
Mediavilla-Varela M, Pacheco FJ, Almaguel F, et al. (2009) Docetaxel-induced prostate cancer cell death involves concomitant activation of caspase and lysosomal pathways and is attenuated by LEDGF/p75. Molecular Cancer. 8: 68
Khan S, Aspe JR, Asumen MG, et al. (2009) Extracellular, cell-permeable survivin inhibits apoptosis while promoting proliferative and metastatic potential British Journal of Cancer. 100: 1073-1086
Almaguel FG, Liu JW, Pacheco FJ, et al. (2009) Activation and reversal of lipotoxicity in PC12 and rat cortical cells following exposure to palmitic acid. Journal of Neuroscience Research. 87: 1207-18
Liu JW, Almaguel FG, Bu L, et al. (2008) Expression of E-FABP in PC12 cells increases neurite extension during differentiation: involvement of n-3 and n-6 fatty acids. Journal of Neurochemistry. 106: 2015-29
Singh SK, Moretta D, Almaguel F, et al. (2008) Precursor Igf-II (proIGF-II) and mature IGF-II (mIGF-II) induce Bcl-2 and Bcl-XL expression through different signaling pathways in breast cancer cells Growth Factors. 26: 92-103
Kalla Singh S, Moretta D, Almaguel F, et al. (2007) Differential effect of proIGF-II and IGF-II on resveratrol induced cell death by regulating survivin cellular localization and mitochondrial depolarization in breast cancer cells Growth Factors. 25: 363-372
Ulloth JE, Almaguel FG, Padilla A, et al. (2007) Characterization of methyl-beta-cyclodextrin toxicity in NGF-differentiated PC12 cell death. Neurotoxicology. 28: 613-21
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