David Wagner

Marquette University, Milwaukee, WI, United States 
GABA(A) receptor structure-function; GABA(A) receptor kinetics
"David Wagner"
Mean distance: 16.18 (cluster 11)
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Tran PN, Laha KT, Wagner DA. (2011) A tight coupling between β₂Y97 and β₂F200 of the GABA(A) receptor mediates GABA binding. Journal of Neurochemistry. 119: 283-93
Goldschen-Ohm MP, Wagner DA, Jones MV. (2011) Three arginines in the GABAA receptor binding pocket have distinct roles in the formation and stability of agonist- versus antagonist-bound complexes. Molecular Pharmacology. 80: 647-56
Laha KT, Wagner DA. (2011) A state-dependent salt-bridge interaction exists across the β/α intersubunit interface of the GABAA receptor. Molecular Pharmacology. 79: 662-71
Goldschen-Ohm MP, Wagner DA, Petrou S, et al. (2010) An epilepsy-related region in the GABA(A) receptor mediates long-distance effects on GABA and benzodiazepine binding sites. Molecular Pharmacology. 77: 35-45
Wagner DA, Goldschen-Ohm MP, Hales TG, et al. (2005) Kinetics and spontaneous open probability conferred by the epsilon subunit of the GABAA receptor. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 10462-8
Wagner DA, Czajkowski C, Jones MV. (2004) An arginine involved in GABA binding and unbinding but not gating of the GABA(A) receptor. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 2733-41
Kucken AM, Teissére JA, Seffinga-Clark J, et al. (2003) Structural requirements for imidazobenzodiazepine binding to GABA(A) receptors. Molecular Pharmacology. 63: 289-96
Bowser DN, Wagner DA, Czajkowski C, et al. (2002) Altered kinetics and benzodiazepine sensitivity of a GABAA receptor subunit mutation [gamma 2(R43Q)] found in human epilepsy. Proceedings of the National Academy of Sciences of the United States of America. 99: 15170-5
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