David Wagner
Affiliations: | Marquette University, Milwaukee, WI, United States |
Area:
GABA(A) receptor structure-function; GABA(A) receptor kineticsWebsite:
http://biology.marquette.edu/faculty/wagner.htmlGoogle:
"David Wagner"Mean distance: 16.18 (cluster 11) | S | N | B | C | P |
Children
Sign in to add trainee| Ali L. Althaus | research assistant | 2001-2002 | Marquette University |
| Kurt Laha | grad student | 2011 | Marquette University |
| Phu N. Tran | grad student | 2011 | Marquette University |
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Publications
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| Tran PN, Laha KT, Wagner DA. (2011) A tight coupling between β₂Y97 and β₂F200 of the GABA(A) receptor mediates GABA binding. Journal of Neurochemistry. 119: 283-93 |
| Goldschen-Ohm MP, Wagner DA, Jones MV. (2011) Three arginines in the GABAA receptor binding pocket have distinct roles in the formation and stability of agonist- versus antagonist-bound complexes. Molecular Pharmacology. 80: 647-56 |
| Laha KT, Wagner DA. (2011) A state-dependent salt-bridge interaction exists across the β/α intersubunit interface of the GABAA receptor. Molecular Pharmacology. 79: 662-71 |
| Goldschen-Ohm MP, Wagner DA, Petrou S, et al. (2010) An epilepsy-related region in the GABA(A) receptor mediates long-distance effects on GABA and benzodiazepine binding sites. Molecular Pharmacology. 77: 35-45 |
| Wagner DA, Goldschen-Ohm MP, Hales TG, et al. (2005) Kinetics and spontaneous open probability conferred by the epsilon subunit of the GABAA receptor. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 10462-8 |
| Wagner DA, Czajkowski C, Jones MV. (2004) An arginine involved in GABA binding and unbinding but not gating of the GABA(A) receptor. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 2733-41 |
| Kucken AM, Teissére JA, Seffinga-Clark J, et al. (2003) Structural requirements for imidazobenzodiazepine binding to GABA(A) receptors. Molecular Pharmacology. 63: 289-96 |
| Bowser DN, Wagner DA, Czajkowski C, et al. (2002) Altered kinetics and benzodiazepine sensitivity of a GABAA receptor subunit mutation [gamma 2(R43Q)] found in human epilepsy. Proceedings of the National Academy of Sciences of the United States of America. 99: 15170-5 |
| Horenstein J, Wagner DA, Czajkowski C, et al. (2001) Protein mobility and GABA-induced conformational changes in GABA(A) receptor pore-lining M2 segment. Nature Neuroscience. 4: 477-85 |
| Wagner DA, Czajkowski C. (2001) Structure and Dynamics of the GABA Binding Pocket: A Narrowing Cleft that Constricts during Activation The Journal of Neuroscience. 21: 67-74 |