Jaime H. Cheah, Ph.D.

Affiliations: 
2006 Johns Hopkins University, Baltimore, MD 
Area:
Neurotransmitters
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"Jaime Cheah"
Mean distance: 14.4 (cluster 40)
 
SNBCP

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Solomon H. Snyder grad student 2006 Johns Hopkins
 (Behind the iron curtain: Dexras1 mediates glutamate-NMDA induced neuronal iron uptake.)
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Publications

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Hong AL, Tseng YY, Cowley GS, et al. (2016) Integrated genetic and pharmacologic interrogation of rare cancers. Nature Communications. 7: 11987
Yard BD, Adams DJ, Chie EK, et al. (2016) A genetic basis for the variation in the vulnerability of cancer to DNA damage. Nature Communications. 7: 11428
Adams DJ, Ito D, Rees MG, et al. (2014) NAMPT is the cellular target of STF-31-like small-molecule probes. Acs Chemical Biology. 9: 2247-54
Yang WS, SriRamaratnam R, Welsch ME, et al. (2014) Regulation of ferroptotic cancer cell death by GPX4. Cell. 156: 317-31
Choi BR, Bang S, Chen Y, et al. (2013) PKA modulates iron trafficking in the striatum via small GTPase, Rhes. Neuroscience. 253: 214-20
Basu A, Bodycombe NE, Cheah JH, et al. (2013) An interactive resource to identify cancer genetic and lineage dependencies targeted by small molecules. Cell. 154: 1151-61
Chen Y, Khan RS, Cwanger A, et al. (2013) Dexras1, a small GTPase, is required for glutamate-NMDA neurotoxicity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 3582-7
Dinkova-Kostova AT, Cheah J, Samouilov A, et al. (2007) Phenolic Michael reaction acceptors: Combined direct and indirect antioxidant defenses against electrophiles and oxidants Medicinal Chemistry. 3: 261-268
Cheah JH, Kim SF, Hester LD, et al. (2006) NMDA receptor-nitric oxide transmission mediates neuronal iron homeostasis via the GTPase Dexras1. Neuron. 51: 431-40
Hara MR, Agrawal N, Kim SF, et al. (2005) S-nitrosylated GAPDH initiates apoptotic cell death by nuclear translocation following Siah1 binding. Nature Cell Biology. 7: 665-74
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