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Eduarta Holl, Ph.D.

Affiliations: 
2010 Microbiology & Immunology University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Neuroinflammation
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"Eduarta Holl"
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Jenny P-Y Ting grad student 2010 UNC Chapel Hill
 (The role of plexin-D1 in the adaptive immune system: Implications for humoral immunity.)

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Publications

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Brown MC, Mosaheb MM, Mohme M, et al. (2021) Viral infection of cells within the tumor microenvironment mediates antitumor immunotherapy via selective TBK1-IRF3 signaling. Nature Communications. 12: 1858
Brown MC, Holl EK, Boczkowski D, et al. (2017) Cancer immunotherapy with recombinant poliovirus induces IFN-dominant activation of dendritic cells and tumor antigen-specific CTLs. Science Translational Medicine. 9
Holl EK, Shumansky KL, Pitoc G, et al. (2013) Nucleic acid scavenging polymers inhibit extracellular DNA-mediated innate immune activation without inhibiting anti-viral responses. Plos One. 8: e69413
Roney K, Holl E, Ting J. (2013) Immune plexins and semaphorins: old proteins, new immune functions. Protein & Cell. 4: 17-26
Holl EK, Roney KE, Allen IC, et al. (2012) Plexin-B2 and Plexin-D1 in dendritic cells: expression and IL-12/IL-23p40 production. Plos One. 7: e43333
Schneider M, Zimmermann AG, Roberts RA, et al. (2012) The innate immune sensor NLRC3 attenuates Toll-like receptor signaling via modification of the signaling adaptor TRAF6 and transcription factor NF-κB. Nature Immunology. 13: 823-31
Roney KE, O'Connor BP, Wen H, et al. (2011) Plexin-B2 negatively regulates macrophage motility, Rac, and Cdc42 activation. Plos One. 6: e24795
Holl EK, O'Connor BP, Holl TM, et al. (2011) Plexin-D1 is a novel regulator of germinal centers and humoral immune responses. Journal of Immunology (Baltimore, Md. : 1950). 186: 5603-11
Allen IC, TeKippe EM, Woodford RM, et al. (2010) The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer. The Journal of Experimental Medicine. 207: 1045-56
Allen IC, Scull MA, Moore CB, et al. (2009) The NLRP3 inflammasome mediates in vivo innate immunity to influenza A virus through recognition of viral RNA. Immunity. 30: 556-65
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